Name Ibuprofen
Classes Analgesic / Pain Killer
Central Nervous System Agent
Diseases Arthritis
Inflammatory Disease


Ibuprofen is a medication in the nonsteroidal anti-inflammatory drug class that is used for treating pain, fever, and inflammation.

Ibuprofen is indicated for the following conditions-

  • Relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis
  • Mild to moderate pain
  • Primary dysmenorrhea
  • Rheumatoid arthritis and osteoarthritis, including flare-ups of chronic disease
    • Suggested Dosage: 1200 mg-3200 mg daily (300 mg 4x a day; 400 mg, 600 mg or 800 mg 3x a day or 4x a day). Individual patients may show a better response to 3200 mg daily, as compared with 2400 mg, although in well-controlled clinical trials patients on 3200 mg did not show a better mean response in terms of efficacy. Therefore, when treating patients with 3200 mg/day, the physician should observe sufficient increased clinical benefits to offset potential increased risk.
  • Mild to moderate pain: 400 mg every 4 to 6 hours as necessary for relief of pain.
  • Dysmenorrhea: For the treatment of dysmenorrhea, beginning with the earliest onset of such pain, Ibuprofen tablets should be given in a dose of 400 mg every 4 hours as necessary for the relief of pain.

Side effects commonly associated with ibuprofen include-

  • Nausea
  • Epigastric pain
  • Vomiting
  • Heat burn
  • Gastritis
  • Dizziness
  • Rash


  • Gastrointestinal disorders and chronic inflammatory intestinal disease as these conditions may be exacerbated (ulcerative colitis, Crohn's disease).
  • Systemic lupus erythematosus as well as those with mixed connective tissue disease due to increased risk of aseptic meningitis.
  • Caution is required prior to starting treatment in patients with a history of hypertension and or heart/failure. Oedema, hypertension and/or cardiac impairment as renal function may deteriorate and/or fluid retention occur.
  • Renal impairment as renal function may deteriorate.


Contraindicated in patients with known hypersensitivity to Ibuprofen.

  • Ibuprofen should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
  • Contraindicated for the treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery.