Diseases
Dexibuprofen (S Ibuprofen)
Dexibuprofen is a medication in the nonsteroidal anti-inflammatory drug class that is used for treating pain, fever, and inflammation.
Ibuprofen is indicated for the following conditions-
- Relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis
- Mild to moderate pain
- Primary dysmenorrhea
- Rheumatoid arthritis and osteoarthritis, including flare-ups of chronic disease
- Suggested Dosage: 1200 mg-3200 mg daily (300 mg 4x a day; 400 mg, 600 mg or 800 mg 3x a day or 4x a day). Individual patients may show a better response to 3200 mg daily, as compared with 2400 mg, although in well-controlled clinical trials patients on 3200 mg did not show a better mean response in terms of efficacy. Therefore, when treating patients with 3200 mg/day, the physician should observe sufficient increased clinical benefits to offset potential increased risk.
- Mild to moderate pain: 400 mg every 4 to 6 hours as necessary for relief of pain.
- Dysmenorrhea: For the treatment of dysmenorrhea, beginning with the earliest onset of such pain, Ibuprofen tablets should be given in a dose of 400 mg every 4 hours as necessary for the relief of pain.
Side effects commonly associated with dexibuprofen include-
- Nausea
- Epigastric pain
- Vomiting
- Heat burn
- Gastritis
- Dizziness
- Rash
- Gastrointestinal disorders and chronic inflammatory intestinal disease as these conditions may be exacerbated (ulcerative colitis, Crohn's disease).
- Systemic lupus erythematosus as well as those with mixed connective tissue disease due to increased risk of aseptic meningitis.
- Caution is required prior to starting treatment in patients with a history of hypertension and or heart/failure. Oedema, hypertension and/or cardiac impairment as renal function may deteriorate and/or fluid retention occur.
- Renal impairment as renal function may deteriorate.
Contraindication
Contraindicated in patients with known hypersensitivity to dexibuprofen.
- Dexibuprofen should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
- Contraindicated for the treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery.