Medicine details

ImageOcubac-D
NameOcubac-D
DosageEye Drops
Generic NameChloramphenicol + Dexamethasone
Classes Dermatological/Topical Agent
Topical Antiinfective Agent
Ophthalmic Preparation
Antiinfective and Steroid Combination
Diseases Allergy
Occular Infection
Ophthalmic Disease
CompanyApex Pharmaceuticals Ltd.

Drug Package Details

Strength5 mg + 1 mg/ml
Storage Condition
Origin CountryBangladesh
Commercial Pack1
Price per pack60.00
Cost per pack52.80
Package unit5 ml drops
Price per unit60.00
Cost per unit52.80
Discount0
Coupon
Remarks

Chloramphenicol + Dexamethasone

Chloramphenicol + Dexamethasone is combination medication for ophthalmic and otic administration. Chloramphenicol is a bacteriostatic antibiotic belonging from the aminoglycosides class. Dexamethasone is an anti-inflammatory drug from the gluco-corticoid class.

Chloramphenicol + Dexamethasone is indicated for the following conditions-

  • Bacterial Infection of the eye
  • Conjunctivitis
  • Keratitis
  • Eye inflammation
  • Corneal ulcer
  • Otitis
 

 

Eye

  • Bacterial Conjunctivitis: For the treatment of bacterial conjunctivitis, 1 to 2 drops instilled into the conjunctival sac (s) every 2 hours for 2 days, followed by 1 or 2 drops every 4 hours for the next 5 (five days) while awake.
  • Corneal Ulcers: The recommended dosage regimen for the treatment of corneal ulcers is two drops in the affected eye(s) every 15 minutes for the first six hours, followed by two drops in the affected eye(s) every 30 minutes for the remainder of the first day. On the second day, place two drops in the affected eye (s) every hour. Place 2 drops in the affected eye (s) every 4 hours for 3 to 14 days. Treatment may be continued after 14 days if corneal re-epithelialization has not occurred.

Ear

  • For all infections, 2 to 3 drops every 2 to 3 hours initially. Frequency should be decreased gradually as warranted by improvement in clinical signs. Care should be taken not to discontinue therapy prematurely.

Chloramphenicol + Dexamethasone may cause the following side effects-

  • Eye burning
  • Eye redness
  • Blurred vision
  • Photophobia
  • Eye dryness
  • After prolonged corticosteroid dosing, the possibility of persistent fungal infections of the cornea should be considered.
  • Prolonged use of steroid-containing products may result in the formation of posterior subcapsular cataracts and glaucoma with optic nerve damage. Monitoring of intraocular pressure is required.
  • Antibiotic use for an extended period of time may result in the overgrowth of non-susceptible organisms, including fungi. If new infections develop during treatment, the drug should be stopped and alternative therapy should be started.

Contraindication

Contraindicated in individuals with known or suspected hypersensitivity to any of the ingredients of this preparation and to other corticosteroids, such as-

Contraindicated in most viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, and also in mycobacterial infection of the eye and fungal diseases of ocular structures.