Medicine details
| Image |  |
| Name | Lora PLUS 10/240 |
| Dosage | Tablet |
| Generic Name | Loratadine + Pseudoephedrine Hydrochloride |
| Classes |
Respiratory Agent Antiallergic Agent Antihistamine Combination |
| Diseases |
Allergic Reaction Cold Hive Itching Skin Rash Sneezing Watery Eye |
| Company | Opsonin Pharma Limited |
Drug Package Details
| Strength | 10 mg + 240 mg |
| Storage Condition | |
| Origin Country | Bangladesh |
| Commercial Pack | 30 |
| Price per pack | ৳ 180.60 |
| Cost per pack | ৳ 158.93 |
| Package unit | 10 tabs strip |
| Price per unit | ৳ 6.02 |
| Cost per unit | ৳ 5.30 |
| Discount | 0 |
| Coupon | |
| Remarks |
Loratadine + Pseudoephedrine Hydrochloride
Loratadine is an anti-allergic histamine H1-receptor antagonist that is non-sedative. Loratadine is a long-acting tricyclic antihistamine with selective peripheral H1-receptor antagonistic activity but no sedative or anticholinergic effects.
Pseudoephedrine is a sympathomimetic amine that acts as a decongestant on the nasal mucosa when taken orally. This is known to be an excellent treatment for nasal congestion caused by allergic rhinitis. It works as a nasal and bronchial decongestant.
- Loratadine + pseudoephedrine sulfate extended release tablets should be administered when both the antihistaminic properties of loratadine and the nasal decongestant activity of pseudoephedrine are desired.
- Loratadine + pseudoephedrine sulfate extended release tablets are indicated for the relief of symptoms of-
Adults and Children 12 Years of Age and Over:
- 12 Hour Tablet: One tablet twice a day (every 12 hours)
- 24 Hour Tablet: One tablet daily taken with a full glass of water.
- Because the doses of this fixed combination product cannot be individually titrated and hepatic insufficiency results in a reduced clearance of loratadine to a much greater extent than pseudoephedrine, loratadine; pseudoephedrine sulfate extended release tablets should generally be avoided in patients with hepatic insufficiency. Patients with renal insufficiency (GFR <30 ml/min) should be given a lower initial dose (one 12 hour tablet per day, or one 24 hour tablet every other day) because they have reduced clearance of loratadine and pseudoephedrine. Patients who have a history of difficulty in swallowing tablets or who have known upper gastrointestinal narrowing or abnormal esophageal peristalsis should not use the 24 hour tablet.
Commonly reported side effects of Loratadine + pseudoephedrine sulfate include-
- Headache
- Somnolence
- Fatigue/ Asthenia
- Dry mouth
- Nervousness
- Dyspepsia
- Nausea
- In individuals with hypertension, diabetes mellitus, ischemic heart disease, elevated intraocular pressure, hyperthyroidism, renal impairment, or prostatic hypertrophy, loratadine + pseudoephedrine sulfate extended release tablets should be taken with caution. Sympathomimetic amines can cause central nervous system excitement and convulsions, as well as cardiovascular collapse and hypotension.
- Patients aged 60 and up: In placebo-controlled clinical trials, the safety and efficacy of loratadine + pseudoephedrine sulfate extended release tablets in patients over 60 years old have not been examined. Sympathomimetic amines are more prone to cause unpleasant responses in the elderly.
Contraindication
- Patients who are hypersensitive to this drug or any of its constituents should not take loratadine + pseudoephedrine sulfate extended release tablets.
- Contraindicated in patients receiving monoamine oxidase (MAO) inhibitor therapy or within fourteen (14) days of stopping such treatment.
There is no known contraindications of Loratadine + pseudoephedrine sulfate in terms of food and drinks.
Patients with narrow-angle glaucoma or urinary retention should avoid this medicine because it contains pseudoephedrine.
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