Medicine details

ImageABO Kit
NameABO Kit
DosageTablet
Generic NameMifepristone + Misoprostol
Classes Hormone Inhibitor
Hormone Inhibitor Combination
Diseases
CompanyGlobe Pharmaceuticals Ltd.

Drug Package Details

Strength200 mg + 200 mcg
Storage Condition
Origin CountryBangladesh
Commercial Pack5
Price per pack280.00
Cost per pack246.40
Package unit5 tabs strip
Price per unit56.00
Cost per unit49.28
Discount0
Coupon
Remarks

Mifepristone + Misoprostol

Mifepristone + Misoprostol is a combination of two medications used for medical abortion. Mifepristone is a progesterone receptor antagonist that blocks the action of progesterone, a hormone necessary for maintaining pregnancy. Misoprostol is a prostaglandin analog that causes uterine contractions and helps to expel the pregnancy.

 

  • Mifepristone + Misoprostol is indicated for the medical termination of intrauterine pregnancy up to 70 days of gestation.
  • It is also used for the induction of labor in cases of fetal death in utero or when the pregnancy poses a risk to the mother's health.

200mg of mifepristone (one tablet) is taken in a single oral dose, followed 36 to 48 hours later, by the administration of misoprostol 800 micrograms (i.e. 4 vaginal tablets of 0.2mg each) vaginally in a single dose. If the patient vomits shortly after administration of mifepristone, she should inform the doctor.

Method of administration

Misoprostol vaginal tablets can be administered by a health care provider (place two tablets on each side of the cervix in vaginal vault) or by the woman herself. The woman should be instructed to clean her hands thoroughly before inserting the misoprostol vaginal tablets as high as possible into the vagina, and remain recumbent for at least 30 minutes

 

The following side effects may occur with Mifepristone + Misoprostol- 

  • Vaginal bleeding and spotting
  • Abdominal pain and cramping
  • Nausea and vomiting
  • Diarrhea
  • Dizziness and headache
  • Fatigue
  • Fever and chills

 

  • Ectopic pregnancy: Mifepristone + Misoprostol is not intended for use in cases of ectopic pregnancy (pregnancy outside the uterus). The presence of an ectopic pregnancy should be ruled out before initiating treatment.
  • Hemorrhage: Vaginal bleeding is expected after using Mifepristone + Misoprostol. However, if the bleeding is excessive or persists for an extended period, medical attention should be sought as it may indicate the need for further evaluation or intervention.
  • Incomplete abortion: In some cases, the medical abortion may be incomplete, requiring additional medical or surgical intervention to ensure the termination of the pregnancy.
  • Infection: There is a risk of infection following a medical abortion. Patients should be advised to watch for signs of infection, such as fever, abnormal vaginal discharge, or pelvic pain, and to seek medical attention if these symptoms occur.
  • Contraception: Mifepristone + Misoprostol does not provide contraceptive protection. Patients should be advised to use reliable contraception following the procedure to prevent unintended pregnancies.

 

Contraindication

Hypersensitivity to the active substances or to any of the excipients.

 

This product SHOULD NEVER be prescribed in the following situations:

  • pregnancy not confirmed by gynecological examination, ultrasound scan or biological tests
  • pregnancy beyond 63 days of amenorrhea
  • confirmed or suspected extra-uterine pregnancy
  • severe asthma uncontrolled by therapy
  • inherited porphyria,
  • chronic adrenal failure