Medicine details

ImageApitac
NameApitac
DosageTablet
Generic NameAceclofenac
Classes Analgesic / Pain Killer
Central Nervous System Agent
NSAID
Diseases Ankylosing Spondylitis
Fever
Inflammatory Disease
Osteoarthritis
Pain
CompanyAcme Laboratories Ltd.

Drug Package Details

Strength100 mg
Storage Condition
Origin CountryBangladesh
Commercial Pack100
Price per pack398.60
Cost per pack350.77
Package unit10 tabs strip
Price per unit3.99
Cost per unit3.51
Discount0
Coupon
Remarks

Aceclofenac

Aceclofenac sodium is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, and antipyretic activities. The mechanism of action of diclofenac, like that of other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition.

Aceclofenac is indicated in-

  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis

The recommended daily dose is 200 mg, divided into two 100 mg doses, one in the morning and one in the evening.

  • Body as a Whole: fever, infection, sepsis
  • Cardiovascular System:  congestive heart failure, hypertension, tachycardia, syncope
  • Digestive System: dry mouth, esophagitis, gastric/peptic ulcers, gastritis, gastrointestinal bleeding, glossitis, hematemesis, hepatitis, jaundice
  • Hemic and Lymphatic System:  ecchymosis, eosinophilia, leukopenia, melena, purpura, rectal bleeding, stomatitis, thrombocytopenia
  • Metabolic and Nutritional: weight changes
  • Nervous System:  anxiety, asthenia, confusion, depression, dream abnormalities, drowsiness, insomnia, malaise, nervousness, paresthesia, somnolence, tremors, vertigo
  • Respiratory System:  asthma, dyspnea
  • Skin and Appendages:  alopecia, photosensitivity, sweating increased  
  • Special Senses: blurred vision
  • Urogenital System:  cystitis, dysuria, hematuria, interstitial nephritis, oliguria/polyuria, proteinuria, renal failure
  • Aceclofenac should not be taken with other NSAIDs, including cyclooxygenase-2 selective inhibitors.
  • The elderly are more likely to have adverse reactions to NSAIDs, particularly gastrointestinal bleeding and perforation, which can be fatal.
  • If administered to patients suffering from or with a history of bronchial asthma, use caution because NSAIDs have been shown to precipitate bronchospasm in these patients.
  • An NSAID may cause a dose-dependent decrease in prostaglandin formation and precipitate renal failure. Patients with impaired renal function, cardiac impairment, liver dysfunction, those taking diuretics or recovering from major surgery, and the elderly are most at risk of this reaction. The importance of prostaglandins in maintaining renal blood flow should be considered in these patients.

 

Contraindication

  • Contraindicated in patients with known hypersensitivity to aceclofenac.  
  • Diclofenac sodium should not be given to patients who have experienced asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs, such as-

Aceclofenac is contraindicated in-

  • Peptic ulcer
  • Active bleeding
  • History of gastrointestinal bleeding or perforation
  • Patients with established congestive heart failure (NYHA II-IV), ischaemic heart disease, peripheral arterial disease and/or cerebrovascular disease.