Medicine details

ImageOdeson IM/IV
NameOdeson IM/IV
DosageIV/IM Injection
Generic NameDexamethasone Sodium Phosphate
Classes Dermatological/Topical Agent
Ophthalmic Preparation
Glucocorticoid
Hormone
Diseases Asthma
Bowel Disorder
Breathing Problem
Dermatitis
Hypersensitivity
Inflammatory Disease
Lupus
Psoriasis
Rhinitis
Sclerosis
Ulcerative Colitis
CompanyBeximco Pharmaceuticals Ltd.

Drug Package Details

Strength4mg/ml
Storage Condition
Origin CountryBangladesh
Commercial Pack10
Price per pack150.00
Cost per pack132.00
Package unit1 ml amp
Price per unit15.00
Cost per unit13.20
Discount0
Coupon
Remarks

Dexamethasone Sodium Phosphate

Dexamethasone sodium phosphate belongs to a class of drugs, called the glucocorticoids. It is a synthetic glucocorticoid. Natural glucocorticoids (hydrocortisone and cortisone), which have salt-retaining characteristics, are employed in adrenocortical deficit replacement therapy. Their synthetic analogs are largely employed for anti-inflammatory actions in a variety of organ system illnesses.

Glucocorticoids have a wide range of metabolic consequences. Furthermore, they alter the immune system's reaction to a variety of stimuli.

Dexamethasone sodium phosphate is usually used topically as eye, ear and nasal drops. It is also available as tablets, injection to be used systemically.

  • After clinical exclusion of bacterial, viral, or fungal infections, short-term treatment of steroid responsive inflammatory diseases of the eye.
  • Inflammation of the ear or nose that is not infectious.

As eye drops:

  • As 0.1% drop: Depending on the severity of the underlying problem and the response to treatment, the frequency of instillation of drops and the duration of treatment will vary. In order to achieve a decent response, one to two drops must be injected into the eye every thirty to sixty minutes. If there is no response, subconjunctival or systemic steroid therapy should be attempted. Reduce the dosage to one drop every four hours once a positive reaction has been noted.
  • As 0.05% ointment: Up to four times each day, apply a 0.5-1 inch ribbon of ointment to the conjunctival sac(s). Once the condition has improved, reduce the dosage to once daily.

As ear drops:

  • At a two- or three-hour interval, apply two or three drops to the ear. The frequency of dosage and treatment length may differ depending on the type of lesion and severity.
  • Nasal
    • Adult: For non-infected cases of the nose: As 0.1% betamethasone Na phosphate drops: Apply 2-3 drops into each nostril twice or thrice a day as required. Use the lowest effective dose for the shortest possible time. Discontinue if there is no clinical response within 7 days of treatment.
  • Ophthalmic
    • Adult: For short-term treatment of steroid-responsive cases: As 0.1% betamethasone Na phosphate drops: Initially, apply 1-2 drops into the affected eye(s) every 1-2 hours, then reduce frequency once the condition is under control. As 0.1% betamethasone Na phosphate ointment: Apply 2-4 times daily; alternatively, doses may be applied at night. Use the lowest effective dose for the shortest possible time. Discontinue if there is no clinical response within 7 days of treatment.
Eye Drops
Ear Drops

Dexamethasone sodium phosphate can cause the following side effects-

  • irritation
  • burning
  • stinging
  • itching
  • dermatitis
  • corneal ulceration
  • posterior subcapsular cataracts (prolonged use)
  • keratitis
  • Undiagnosed red eyes should never be treated with topical corticosteroids.
  • Ophthalmic treatment with corticosteroid preparations should not be repeated or continued without regular monitoring to rule out increased intraocular pressure, cataract formation, or infection.

Contraindication

Contraindicated in patients hypersensitive to dexamethasone or other glucocorticoids, such as-

There is no known contraindications of methyl prednisolone in terms of food and drinks.

Contraindicated in patients with systemic fungal infection.