Medicine details

ImageZopilone 2
NameZopilone 2
DosageTablet
Generic NameEszopiclone
Classes Central Nervous System Agent
Psychotherapeutic Agent
Anxiolytic
Sedative and Hypnotic
Diseases CNS Disorder
Sleeping Disorder
CompanyIncepta Pharmaceuticals Ltd.

Drug Package Details

Strength2 mg
Storage Condition
Origin CountryBangladesh
Commercial Pack50
Price per pack150.00
Cost per pack132.00
Package unit10 tabs strip
Price per unit3.00
Cost per unit2.64
Discount0
Coupon
Remarks

Eszopiclone

Eszopiclone is non benzodiazepine GABA-A agonist.  GABA receptors when stimulated produces inhibitory effects on other neuronal signals.

 

Eszopiclone is indicated for insomnia to improve and maintain quality sleep.

 

  • The lowest dose effective for the patient should be used,
  • Recommended initial dose is 1 mg, immediately before bedtime, with at least 7-8 hours remaining before the planned time of awakening. May increase dose if clinically indicated, to a maximum of 3 mg  
  • Geriatric or debilitated patients: Dose should not exceed 2 mg
  • Patients with severe hepatic impairment, or taking potent CYP3A4 inhibitors: Dose should not exceed 2 mg
  • Do not take with or immediately after a meal 

 

 

Commonly reported side effects are-

  • Taste disturbances
  • Headache
  • Somnolence
  • Respiratory infection
  • Dizziness
  • Dry mouth
  • Rash 
  • Anxiety
  • Hallucinations

 

  • Effects of CNS depressants include impaired alertness and motor coordination, as well as the risk of morning impairment. The risk rises with the dose. Patients taking 3 mg should be advised not to drive or engage in activities requiring complete mental alertness the morning after use.
  • Examine for Co-Morbid Conditions: Reevaluate if insomnia persists after 7 to 10 days of treatment.
  • Severe Anaphylactic/Anaphylactoid Reactions (including angioedema and anaphylaxis): If such reactions occur, do not re-challenge.
  • Abnormal Thinking, Behavioral Changes (such as hallucinations), and Complex Behaviors (such as "sleep-driving"): If this happens, you should evaluate it right away.
  • A worsening of depression or suicidal ideation is possible: To avoid intentional overdose, prescribe the fewest number of tablets possible.
  • Withdrawal Symptoms: Symptoms may occur if the dose is reduced or stopped abruptly.
  • Elderly Patients: Use lower dose due to impaired motor, cognitive performance and increased sensitivity.
  • Patients with hepatic impairment, impaired respiratory function, impaired drug metabolism or hemodynamic responses: Use with caution.

 

 

Contraindication

Known hypersensitivity to eszopiclone.

 

There is no known contraindications of eszopiclone in terms of health condition.