Medicine details

ImageFebustat 40
NameFebustat 40
DosageTablet
Generic NameFebuxostat
Classes
Diseases Blood Disorder
Gout
Hyperuricemia
CompanyIncepta Pharmaceuticals Ltd.

Drug Package Details

Strength40 mg
Storage Condition
Origin CountryBangladesh
Commercial Pack30
Price per pack360.00
Cost per pack316.80
Package unit10 tabs strip
Price per unit12.00
Cost per unit10.56
Discount0
Coupon
Remarks

Febuxostat

Febuxostat is a xanthine oxidase inhibitor. It works by blocking the action of the enzyme xanthine oxidase, which is responsible for the production of uric acid in the body. By reducing the production of uric acid, Febuxostat helps lower the levels of uric acid in the blood and prevent the formation of uric acid crystals, which are the main cause of gout.

 

Febuxostat is indicated for the chronic management of hyperuricemia in patients with gout.

 

  • The recommended starting dose of Febuxostat is 40 mg once daily.
  • The maximum recommended dose is 80 mg once daily.
  • The dose may be adjusted based on individual patient response and tolerance.
  • Febuxostat should be taken with a meal to improve its absorption.

 

The most common adverse reactions associated with Febuxostat therapy include:

  • liver function test abnormalities
  • nausea
  • joint pain
  • skin rash
  • Other potential adverse reactions include: elevated blood pressure, myalgia, and headache.

 

  • Febuxostat should be used with caution in patients with liver impairment.
  • Febuxostat may increase the risk of cardiovascular events and stroke, especially in patients with pre-existing cardiovascular disease or risk factors.
  • Febuxostat may increase the risk of serious and potentially fatal liver injury, especially in patients with pre-existing liver disease or elevated liver function tests.
  • Febuxostat may increase the risk of serious skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis.

 

Contraindication

Febuxostat is contraindicated in patients with a history of allergy or hypersensitivity to Febuxostat or other xanthine oxidase inhibitors such as-

 

Febuxostat is contraindicated in patients with severe liver problems.