• Allergic States: Asthma, atopic dermatitis, contact dermatitis, drug hypersensitivity reactions,  perennial or seasonal allergic rhinitis, serum sickness, transfusion reactions.
• Dermatologic Diseases: Bullous dermatitis herpetiformis, exfoliative erythroderma, mycosis fungoides, pemphigus, severe erythema multiforme (Stevens-Johnson syndrome).
• Endocrine Disorders: Congenital adrenal hyperplasia, hypercalcemia associated with cancer, nonsuppurative thyroiditis.
• Gastrointestinal Diseases: Regional enteritis and ulcerative colitis.
• Hematologic Disorders: Acquired (autoimmune) hemolytic anemia, Diamond-Blackfan anemia, pure red cell aplasia, selected cases of secondary thrombocytopenia.
• Neoplastic Diseases: For symptomatic relief of Lymphoma and leukemia.
• Nervous System: Acute exacerbations of multiple sclerosis; cerebral edema associated with primary or metastatic brain tumor or craniotomy.
• Ophthalmic Diseases: Sympathetic ophthalmia, temporal arteritis, uveitis and ocular inflammatory conditions unresponsive to topical corticosteroids.
• Renal Diseases: To Induce diuresis or proteinuria remission in patients with idiopathic nephrotic syndrome or lupus erythematosus.
• Respiratory Diseases: Berylliosis, fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate tuberculosis chemotherapy, idiopathic eosinophilic pneumonias, symptomatic sarcoidosis.
• Rheumatic Disorders: As adjunctive therapy for short-term administration in acute gouty arthritis; acute rheumatic carditis; ankylosing spondylitis; psoriatic arthritis; rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy). For the treatment of dermatomyositis, polymyositis, and systemic lupus erythematosus.

Berylliosis	Pulmonary sarcoidosis	Leukemia	Psoriatic Arthritis
Gout	Thyroiditis	Ulcerative Colitis	Dermatitis

Depending on the disease condition being treated, the first dosage of Hydrocortisone Tablets can range from 20 mg to 240 mg of hydrocortisone per day. Lower doses are usually sufficient in less severe conditions, however higher first doses may be required in some people. The first dosage should be kept the same or increased until a good reaction is observed. Hydrocortisone should be stopped and the patient switched to another acceptable medication if there is no good clinical response after a reasonable period of time.

IT SHOULD BE REMEMBERED THAT DOSAGE REQUIREMENTS VARY AND MUST BE INDIVIDUALIZED BASED ON THE DISEASE UNDER TREATMENT AS WELL AS THE PATIENT'S RESPONSE.

Hydrocortisone can cause the following side effects-

• Congestive heart failure in susceptible patients
• Hypertension
• Edema
• Hypokalemia
• Hypokalemic alkalosis
• Muscle weakness
• Loss of muscle mass
• Steroid myopathy
• Osteoporosis
• Peptic ulcer with possible perforation and hemorrhage
• Pancreatitis
• Abdominal distention
• Ulcerative esophagitis
• Increased sweating
• Development of Cushingoid state
• Suppression of growth in children
• Secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness
• Menstrual irregularities
• Decreased carbohydrate tolerance
• Manifestations of latent diabetes mellitus

Hypertension (Hight Blood Pressure)	Edema	Hypokalemia (Low Potassium)
Pancreatitis	Osteoporosis (Brittle Bone)	Excessive Sweating (Hyperhidrosis)

• Some indications of infection may be hidden by corticosteroids, and new infections may develop as a result of their use. Infections with any pathogen, including viral, bacterial, fungal, protozoan, or helminthic infections, may be linked to the use of corticosteroids alone or in combination with other immunosuppressive agents that affect cellular immunity, humoral immunity, or neutrophil function, in any part of the body.
• The risk of drug-induced secondary adrenocortical insufficiency can be reduced by gradually lowering the dosage. This form of relative insufficiency can last for months after you stop taking hormone therapy, therefore if you have a stressful circumstance during that time, hormone therapy should be resumed.
• Corticosteroids have a stronger effect on hypothyroidism patients and those with cirrhosis.
• Because of the risk of corneal perforation, corticosteroids should be taken with caution in individuals with ocular herpes simplex.
• To regulate the condition being treated, the lowest possible amount of corticosteroid should be utilized, and when dosage reduction is possible, it should be done gradually.
• In individuals with systemic sclerosis, caution is advised since corticosteroids, particularly methylprednisolone, have been linked to an increased risk of scleroderma renal crisis.
• If there is a risk of impending perforation, abscess, or other pyogenic infection, steroids should be used with caution in nonspecific ulcerative colitis; diverticulitis; fresh intestinal anastomoses; active or latent peptic ulcer; renal insufficiency;
• Infants and children receiving long-term corticosteroid medication should have their growth and development monitored closely.