Ibuprofen is indicated for the following conditions-

• Relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis
• Mild to moderate pain
• Primary dysmenorrhea

Arthritis

Pain

Primary dysmenorrhea

• Rheumatoid arthritis and osteoarthritis, including flare-ups of chronic disease
  
  • Suggested Dosage: 1200 mg-3200 mg daily (300 mg 4x a day; 400 mg, 600 mg or 800 mg 3x a day or 4x a day). Individual patients may show a better response to 3200 mg daily, as compared with 2400 mg, although in well-controlled clinical trials patients on 3200 mg did not show a better mean response in terms of efficacy. Therefore, when treating patients with 3200 mg/day, the physician should observe sufficient increased clinical benefits to offset potential increased risk.
• Mild to moderate pain: 400 mg every 4 to 6 hours as necessary for relief of pain.
• Dysmenorrhea: For the treatment of dysmenorrhea, beginning with the earliest onset of such pain, Ibuprofen tablets should be given in a dose of 400 mg every 4 hours as necessary for the relief of pain.

Side effects commonly associated with ibuprofen include-

• Nausea
• Epigastric pain
• Vomiting
• Heat burn
• Gastritis
• Dizziness
• Rash

Epigastric pain

Nausea

Dizziness

Rash

• Gastrointestinal disorders and chronic inflammatory intestinal disease as these conditions may be exacerbated (ulcerative colitis, Crohn's disease).
• Systemic lupus erythematosus as well as those with mixed connective tissue disease due to increased risk of aseptic meningitis.
• Caution is required prior to starting treatment in patients with a history of hypertension and or heart/failure. Oedema, hypertension and/or cardiac impairment as renal function may deteriorate and/or fluid retention occur.
• Renal impairment as renal function may deteriorate.