Medicine details
Image | |
Name | Ketaride |
Dosage | Injection |
Generic Name | Ketamine |
Classes |
Central Nervous System Agent Anesthetic |
Diseases |
Anesthesia Pain |
Company | Incepta Pharmaceuticals Ltd. |
Drug Package Details
Strength | 50 mg/ml |
Storage Condition | |
Origin Country | Bangladesh |
Commercial Pack | 1 |
Price per pack | ৳ 115.00 |
Cost per pack | ৳ 101.20 |
Package unit | 50 mg vial |
Price per unit | ৳ 115.00 |
Cost per unit | ৳ 101.20 |
Discount | 0 |
Coupon | |
Remarks |
Ketamine
Ketamine is a dissociative anesthetic that acts primarily by antagonizing NMDA receptors, leading to its anesthetic and analgesic effects.
Ketamine is indicated in the following conditions-
- Anesthesia: Induction of anesthesia before surgical procedures.
- Analgesia: Management of acute and chronic pain when other analgesic methods are inadequate.
Typical Adult Ketamine Dosage for Anesthesia:
Intravenous Injection (IV):
- Induction: Administer 1 to 4.5 mg/kg IV. Alternatively, give 1 to 2 mg/kg IV at a rate of 0.5 mg/kg/min. A 2 mg/kg dose yields 5 to 10 minutes of surgical anesthesia within 30 seconds.
- Maintenance: Adjust the maintenance dose based on the patient's anesthetic requirements and the use of additional anesthetics. Repeat increments of one-half to the full induction dose as necessary for ongoing anesthesia.
Intramuscular Injection (IM):
- Induction: Administer 6.5 to 13 mg/kg IM. A 9 to 13 mg/kg IM dose provides 12 to 25 minutes of surgical anesthesia.
- Maintenance: Adjust the maintenance dose according to the patient's anesthetic needs and the use of additional anesthetics. Repeat increments of one-half to the full induction dose as necessary for ongoing anesthesia.
Common side effects of ketamine include-
- Increased heart rate (tachycardia).
- Elevated blood pressure.
- Nausea and vomiting.
- Hallucinations.
- Psychiatric Effects:
- Monitor patients for emergency reactions such as hallucinations, nightmares, and confusion.
- Use with caution in patients with a history of psychiatric disorders.
- Respiratory Depression:
- Monitor respiratory function, especially in patients with compromised respiratory status.
- Hypertension and Tachycardia:
- Use with caution in patients with cardiovascular disease.
- Increased Intracranial Pressure:
- Avoid in patients with known or suspected increased intracranial pressure.
Contraindication
Known hypersensitivity to ketamine.
None known.
Contraindicated in severe hypertension.