Ketoprofen is indicated for the management of the signs and symptoms of-

• rheumatoid arthritis and osteoarthritis.
• management of pain
• primary dysmenorrhea

Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals.

Rheumatoid Arthritis

Pain

Osteoarthritis

Primary dysmenorrhea

Arthritis:

• Adult:
  • As conventional cap: 50 mg 4 times daily or 75 mg 3x a day. Max: 300 mg daily. As extended-release cap: 100-200 mg once daily, depending on patient weight and severity of symptoms. Max: 200 mg daily.
• Elderly: Lowest initial and maintenance dose with shortest possible duration.

Dysmenorrhea, Mild to moderate pain:

• Adult: 
  • As conventional cap: 25-50 mg 6-8 hourly as necessary. As extended-release cap: 100-200 mg once daily, depending on patient weight and on severity of symptoms.
• Elderly: Lowest initial and maintenance dose with shortest possible duration.

Commonly reported side effects include-

• Dyspepsia
• nausea
• abdominal pain
• diarrhea
• constipation
• flatulence
• anorexia
• vomiting
• stomatitis
• headache
• insomnia

Dyspepsia	Nausea	Abdominal Pain
Diarrhea	Headache	Insomnia (Difficulty in Falling asleep)

• KETOPROFEN, like other NSAIDs, may cause serious CV side effects, such as MI or stroke, which may result in hospitalization and even death.
• KETOPROFEN like other NSAIDs, can cause GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, which may result in hospitalization and even death.
• Borderline elevations of one or more liver tests may occur in up to 15% of patients taking NSAIDs including KETOPROFEN.
• Anemia is sometimes seen in patients receiving NSAIDs, including KETOPROFEN.
• Patients with asthma may have aspirin-sensitive asthma. The use of aspirin in patients with aspirin-sensitive asthma has been associated with severe bronchospasm which can be fatal. Since cross reactivity, including bronchospasm, between aspirin and other nonsteroidal anti-inflammatory drugs has been reported in such aspirin-sensitive patients, KETOPROFEN should not be administered to patients with this form of aspirin sensitivity and should be used with caution in patients with preexisting asthma.