Medicine details
Image | |
Name | Clarigen |
Dosage | Tablet |
Generic Name | Levocetirizine Hydrochloride |
Classes |
Respiratory Agent Antihistamine Antiallergic Agent |
Diseases |
Allergic Reaction Hive Rash Rhinitis Urticaria |
Company | Drug International Ltd. |
Drug Package Details
Strength | 5 mg |
Storage Condition | |
Origin Country | Bangladesh |
Commercial Pack | 100 |
Price per pack | ৳ 205.00 |
Cost per pack | ৳ 180.40 |
Package unit | 10 tabs strip |
Price per unit | ৳ 2.05 |
Cost per unit | ৳ 1.80 |
Discount | 0 |
Coupon | |
Remarks |
Levocetirizine Hydrochloride
Levocetirizine hydrochloride tablets and oral solution, is an orally active and selective H1-receptor antagonist.
Levocetirizine hydrochloride is indicated for the following conditions-
- Seasonal Allergic Rhinitis
- Perennial Allergic Rhinitis
- Chronic Urticaria
Levocetirizine HCl is available as 2.5 mg/5 mL (0.5 mg/mL) oral solution and as 5 mg breakable (scored) tablets, allowing for the administration of 2.5 mg, if needed. Levocetirizine HCl can be taken without regard to food consumption.
- Adults and Children 12 Years of Age and Older:
Levocetirizine HCl is taken once day in the evening at a dose of 5 mg (1 tablet or 2 teaspoons [10 mL] oral solution). 2.5 mg (1/2 tablet or 1 teaspoon [5 mL] oral solution) once day in the evening may be sufficient for some people. - Children 6 to 11 Years of Age:
The recommended dose of Levocetirizine HCl is 2.5 mg (1/2 tablet or 1 teaspoon [5 mL] oral solution) once daily in the evening. The 2.5 mg dose should not be exceeded because the systemic exposure with 5 mg is approximately twice that of adults. - Dose Adjustment for Renal and Hepatic Impairment
In adults and children 12 years of age and older with:
- Mild renal impairment (creatinine clearance [CLCR] = 50-80 mL/min): a dose of 2.5 mg once daily is recommended.
- Moderate renal impairment (CLCR = 30-50 mL/min): a dose of 2.5 mg once every other day is recommended.
- Severe renal impairment (CLCR = 10-30 mL/min): a dose of 2.5 mg twice weekly (administered once every 3-4 days) is recommended.
- End-stage renal disease patients (CLCR < 10 mL/min) and patients undergoing hemodialysis should not receive Levocetirizine HCl.
- No dose adjustment is needed in patients with solely hepatic impairment. In patients with both hepatic impairment and renal impairment, adjustment of the dose is recommended.
- Mild renal impairment (creatinine clearance [CLCR] = 50-80 mL/min): a dose of 2.5 mg once daily is recommended.
Commonly reported side effects associated with levocetirizine HCl include-
- Somnolence
- Dry mouth
- Asthenia
- Dizziness
- Activities Requiring Mental Alertness: In clinical trials, the occurrence of somnolence has been reported in some patients taking levocetirizine HCl; due caution should therefore be exercised when driving a car or operating potentially dangerous machinery.
- Concurrent use of levocetirizine HCl with alcohol or other CNS depressants should be avoided because additional reductions in alertness and additional impairment of CNS performance may occur.
- Use of levocetirizine HCl in nursing mothers is not recommended.
- Levocetirizine HClis not indicated for children under 6 years of age.
Contraindication
Levocetirizine HCl is contraindicated in those patients with a known hypersensitivity to it or any of its ingredients or-
There is no known contraindications of levocetirizine HCl in terms of food and drinks.
There is no known contraindications of levocetirizine HCl in terms of health condition.