Megestrol Acetate Oral Suspension is indicated for the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS). 

Anorexia

• The recommended adult initial dosage of Megestrol Acetate Oral Suspension is 800 mg/day (20 mL/day).
• Shake container well before using.
• In clinical trials evaluating different dose schedules, daily doses of 400 and 800 mg/day were found to be clinically effective.
• A plastic dosage cup with 10 mL and 20 mL markings is provided for convenience. 

Adverse reactions associated with megestrol acetate are listed below:

• Thromboembolic Events
• Hyperglycemia
• Impaired Wound Healing
• Hypersensitivity Reactions (rash, pruritus)
• Edema
• Hypertension
• Nausea
• Vomiting
• Weight Gain
• Changes in Libido

Thromboembolism	Hyperglycemia (High Blood Sugar)	Edema
Hypertension (High Blood Pressure)	Weight Gain	Nausea

• Thromboembolic Events: Megestrol Acetate has been associated with an increased risk of thromboembolic events. Consider the risk-benefit profile, especially in patients with a history of thromboembolic events.

• Diabetes: Monitor blood glucose levels closely in diabetic patients, as megestrol acetate may cause hyperglycemia.

• Impaired Wound Healing: Use with caution in patients with impaired wound healing or a history of thrombophlebitis.

• Hypersensitivity Reactions: Discontinue megestrol acetate if signs of hypersensitivity reactions occur and initiate appropriate medical treatment.

• Fluid Retention: Monitor patients for signs of fluid retention and congestive heart failure, especially in those with pre-existing cardiac conditions.