Mepyramine Maleate is indicated for the relief of:

• Allergic rhinitis
• Allergic conjunctivitis
• Mild, uncomplicated allergic skin manifestations of urticaria and angioedema

Allergic rhinitis

Allergic Conjunctivitis

Urticaria

Dosage recommendations may vary based on the specific indication and individual patient response.

1. Adults and Children (12 years and older):

   • Oral tablets: 25 to 50 mg every 4 to 6 hours as needed.
   • Parenteral injection: Dosage and frequency determined by the healthcare provider.

2. Children (6 to 12 years):

   • Oral tablets: 12.5 to 25 mg every 4 to 6 hours as needed.
   • Parenteral injection: Dosage and frequency determined by the healthcare provider.

3. Children (2 to 6 years):

   • Oral tablets: 6.25 to 12.5 mg every 4 to 6 hours as needed.
   • Parenteral injection: Dosage and frequency determined by the healthcare provider.

Adverse reactions of mepyramine maleate are listed below from most common to least common:

• Drowsiness
• Dry mouth
• Blurred vision
• Constipation
• Urinary retention
• Dry nose and throat
• Nausea
• Confusion
• Headache
• Fatigue

Drowsiness

Dry Mouth

Blurred vision

Constipation

• Central Nervous System Depression: Mepyramine Maleate may cause drowsiness. Caution patients against engaging in activities requiring mental alertness.
• Anticholinergic Effects: Monitor for anticholinergic effects, especially in older adults, such as urinary retention, constipation, and blurred vision.
• Respiratory Impairment: Use with caution in patients with respiratory conditions, as antihistamines may cause thickening of bronchial secretions.
• Avoid Alcohol and CNS Depressants: Advise patients to avoid alcohol and other central nervous system depressants while taking Mepyramine Maleate.