Naltrexone is indicated for the treatment of opioid dependence and alcohol dependence. It is used as part of a comprehensive treatment program that includes counseling, behavioral therapy, and other support services.

• Naltrexone is available in various formulations, including tablets and extended-release injectable suspension. The dosage and administration will depend on the specific product and the patient's condition.
• For the treatment of opioid dependence, the recommended initial dose of naltrexone is 25 milligrams, followed by a maintenance dose of 50 milligrams per day. The duration of treatment may vary depending on the individual's response and needs.
• For the treatment of alcohol dependence, the recommended dose of naltrexone is 50 milligrams per day. Treatment may be initiated after a period of abstinence, and the duration of treatment may vary depending on the individual's response and needs.

Adverse reactions to naltrexone are generally mild and include-

• nausea
• vomiting
• diarrhea
• headache
• dizziness
• fatigue

Nausea

Diarrhea

Headache

Dizziness

• Naltrexone should be used with caution in patients with liver disease, as it may increase the risk of liver damage.
• Patients receiving naltrexone should be monitored for signs of depression or suicidal ideation, as the drug may cause or exacerbate these symptoms.
• Naltrexone should not be used in patients who are currently using opioids, as it may precipitate withdrawal symptoms.
• Patients receiving naltrexone should be advised to avoid opioid-containing medications, as they may be less effective and could result in overdose.
• Naltrexone should be used with caution in patients with renal impairment, as the drug is primarily excreted through the kidneys.