Medicine details

ImageAnaflex 500
NameAnaflex 500
DosageTablet
Generic NameNaproxen
Classes Analgesic / Pain Killer
Central Nervous System Agent
NSAID
Diseases Ankylosing Spondylitis
Arthritis
Bursitis
Gout
Inflammatory Disease
Menstrual Cramp
Pain
Tendonitis
CompanyACI Limited

Drug Package Details

Strength500 mg
Storage Condition
Origin CountryBangladesh
Commercial Pack30
Price per pack271.80
Cost per pack239.18
Package unit10 tabs strip
Price per unit9.06
Cost per unit7.97
Discount0
Coupon
Remarks

Naproxen

Naproxen is a nonsteroidal anti-inflammatory drug. It works by reducing hormones that cause inflammation and pain in the body.

Naproxen is indicated for the treatment of:

  • rheumatoid arthritis 
  • osteoarthritis 
  • ankylosing spondylitis 
  • tendinitis
  • bursitis 
  • acute gout 
  • primary dysmenorrhea
  • the relief of mild to moderate pain
  • Use the lowest effective dosage for shortest duration consistent with individual patient treatment goals.
  • Rheumatoid arthritis, Osteoarthritis and ankylosing spondylitis: The dosage is two 375 mg or 500 mg tablets once daily, or one 750 mg tablet once daily.
  • Management of Pain, PD, and Acute Tendinitis and Bursitis: The dosage is two 500 mg tablets once daily. For patients requiring greater analgesic benefit, two 750 mg tablets or three 500 mg tablets may be used for a limited period. Thereafter, the total daily dose should not exceed two 500 mg tablets
  • For the treatment of Acute Gout: The dosage is two to three 500 mg tablets once daily on the first day, followed by two 500 mg tablets once daily, until the attack has subsided.

The most frequent adverse events were

  • headache
  • followed by dyspepsia
  • flu syndrome 
  • Cardiovascular Thrombotic Events
  • Liver problems
  • Renal Toxicity
  • Hyperkalemia
  • Hepatotoxicity: Inform patients of warning signs and symptoms of hepatotoxicity. Discontinue if abnormal liver tests persist or worsen or if clinical signs and symptoms of liver disease develop. 
  • Hypertension: Patients taking some antihypertensive medications may have impaired response to these therapies when taking NSAIDs. Monitor blood pressure.
  • Heart Failure and Edema: Avoid use of NAPROXEN in patients with severe heart failure unless benefits are expected to outweigh risk of worsening heart failure.
  • Renal Toxicity: Monitor renal function in patients with renal or hepatic impairment, heart failure, dehydration, or hypovolemia. Avoid use of NAPROXEN in patients with advanced renal disease unless benefits are expected to outweigh risk of worsening renal function.
  • Anaphylactic Reactions: Seek emergency help if an anaphylactic reaction occurs.
  • Exacerbation of Asthma Related to Aspirin Sensitivity: NAPROXEN is contraindicated in patients with aspirin-sensitive. asthma. Monitor patients with preexisting asthma (without aspirin sensitivity).
  • Serious Skin Reactions: Discontinue NAPROXEN at first appearance of skin rash or other signs of hypersensitivity.
  • Premature Closure of Fetal Ductus Arteriosus: Avoid use in pregnant women starting at 30 weeks gestation.
  • Hematologic Toxicity: Monitor hemoglobin or hematocrit in patients with any signs or symptoms of anemia.

Contraindication

Known hypersensitivity (e.g., anaphylactic reactions and serious skin reactions) to naproxen or any components of the drug product.


  • History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs. Severe, sometimes fatal, anaphylactic reactions to NSAIDs have been reported in such patients.
  • In the setting of coronary artery bypass graft (CABG) surgery.