Medicine details

Image RivaXa
Name RivaXa 10
Dosage Tablet
Generic Name Rivaroxaban
Classes Anticoagulant
Coagulation Modifier
Haematological Agent
Diseases Blood Disorder
Deep Vein Thrombosis (DVT)
Pulmonary Embolism
Stroke
Company Square Pharmaceuticals Ltd.

Drug Package Details

Strength 10 mg
Storage Condition
Origin Country Bangladesh
Commercial Pack 100
Price per pack 1.00
Cost per pack 0.88
Package unit 10 tabs strip
Price per unit 0.01
Cost per unit 0.01
Discount 0
Coupon
Remarks

Rivaroxaban

Rivaroxaban is a selective inhibitor of Factor Xa, a coagulation factor that plays a critical role in the blood clotting process. It belongs to the class of anticoagulant drugs known as direct oral anticoagulants (DOACs).

 

Rivaroxaban is indicated for the following uses:

  • To reduce risk of stroke and systemic embolism in nonvalvular atrial fibrillation 
  • For treatment of deep vein thrombosis (DVT) 
  • For treatment of pulmonary embolism (PE)
  • For reduction in the risk of recurrence of DVT or PE
  • For prophylaxis of DVT, which may lead to PE in patients undergoing knee or hip replacement surgery 
  • For prophylaxis of venous thromboembolism (VTE) in acutely ill medical patients 
  • To reduce the risk of major cardiovascular events in patients with coronary artery disease (CAD) 
  • To reduce the risk of major thrombotic vascular events in patients with peripheral artery disease (PAD), including patients after recent lower extremity revascularization due to symptomatic PAD 
  • For treatment of VTE and reduction in the risk of recurrent VTE in pediatric patients from birth to less than 18 years 
  • For thromboprophylaxis in pediatric patients 2 years and older with congenital heart disease after the Fontan procedure

 

  • Nonvalvular Atrial Fibrillation: 15 or 20 mg, once daily with food
  • Treatment of DVT and/or PE: 15 mg orally twice daily with food for the first 21 days followed by 20 mg orally once daily with food for the remaining treatment
  • Reduction in the Risk of Recurrence of DVT and/or PE in patients at continued risk for DVT and/or PE: 10 mg once daily with or without food, after at least 6 months of standard anticoagulant treatment
  • Prophylaxis of DVT Following Hip or Knee Replacement Surgery: 10 mg orally once daily with or without food
  • Prophylaxis of VTE in Acutely Ill Medical Patients at Risk for Thromboembolic Complications Not at High Risk of Bleeding: 10 mg once daily, with or without food, in hospital and after hospital discharge for a total recommended duration of 31 to 39 days
  • CAD or PAD: 2.5 mg orally twice daily with or without food, in combination with aspirin (75-100 mg) once daily
  • Pediatric Patients: See dosing recommendations in the Full Prescribing Information

The following adverse reactions may occur while using Rivaroxaban:

  • Bleeding (most common)
  • Anemia
  • Nausea
  • Headache
  • Dizziness
  • Fatigue

 

  • Risk of bleeding: Rivaroxaban can cause serious and fatal bleeding. An agent to reverse the activity of rivaroxaban is available. 
  • Pregnancy-related hemorrhage: Use Rivaroxaban with caution in pregnant women due to the potential for obstetric hemorrhage and/or emergent delivery. 
  • Prosthetic heart valves: Rivaroxaban use not recommended. 
  • Increased Risk of Thrombosis in Patients with Triple Positive Antiphospholipid Syndrome: Rivaroxaban use not recommended. 

 

Contraindication

Rivaroxaban is contraindicated in hypersensitivity to Rivaroxaban or any of its components.

 

Rivaroxaban is contraindicated in the following conditions:

  • Active pathological bleeding
  • Severe liver impairment