Medicine details
Image | |
Name | Rocovas 10 |
Dosage | Tablet |
Generic Name | Rosuvastatin |
Classes |
Metabolic Agent Antihyperlipidemic/Lipid Lowering Agent Statin |
Diseases |
Atherosclerosis Blocked Heart Vessel Cardiovascular Disease High Cholesterol |
Company | Incepta Pharmaceuticals Ltd. |
Drug Package Details
Strength | |
Storage Condition | |
Origin Country | Bangladesh |
Commercial Pack | 30 |
Price per pack | ৳ 450.00 |
Cost per pack | ৳ 396.00 |
Package unit | 10 tabs strip |
Price per unit | ৳ 15.00 |
Cost per unit | ৳ 13.20 |
Discount | 0 |
Coupon | |
Remarks |
Rosuvastatin
Rosuvastatin is a lipid lowering medication that acts by inhibiting the enzyme HMG Co-A reductase. HMG Co-A reductase is an enzyme essential for the synthesis of cholesterols.
Rosuvastatin is indicated for the following cases-
- Hyperlipidemia
- Prevention of Cardiovascular diseases (myocardial infarction, stroke, angina etc.)
- Coronary heart diseases
- Rosuvastatin is available as 5mg, 10mg, 20mg and 40mg tablets.
- The usual starting dose is 10-20 mg. Rotuvastatin can be administered as a single dose at any time of day, with or without food.
- When initiating Rotuvastatin therapy or switching from another HMG-CoA reductase inhibitor therapy, the appropriate Rotuvastatin starting dose should first be utilized, and only then titrated according to the patient’s response and individualized goal of therapy.
- After initiation or upon titration of Rotuvastatin, lipid levels should be analyzed within 2 to 4 weeks and the dosage adjusted accordingly.
- The 40 mg dose of Rotuvastatin should be used only for those patients who have not achieved their LDL-C goal utilizing the 20 mg dose .
- Skeletal muscle effects (e.g., myopathy and rhabdomyolysis): Risks increase with use of 40 mg dose, advanced age (≥65), hypothyroidism, renal impairment, and combination use with cyclosporine, lopinavir/ritonavir, atazanavir/ritonavir, or certain other lipid-lowering drugs. Advise patients to promptly report unexplained muscle pain, tenderness, or weakness and discontinue Rosuvastatin if signs or symptoms appear.
- Liver enzyme abnormalities and monitoring: Persistent elevations in hepatic transaminases can occur. Monitor liver enzymes before and during treatment.
Contraindication
Rosuvastatin is contraindicated in patients hypersensitive to the medicine itself or other statins, such as-
Rosuvastatin is contraindicated in the following health conditions-
- Liver problems
- Pregnancy
- Lactation