Medicine details
| Image |  |
| Name | Mudiral 50 |
| Dosage | Tablet |
| Generic Name | Sertraline |
| Classes |
Central Nervous System Agent Psychotherapeutic Agent Serotonin Reuptake Inhibitor (SRI) |
| Diseases |
Anxiety CNS Disorder Depression Obsessive Compulsive Disorder (OCD) Panic Attack Post Traumatic Stress Premenstrual Dystrophy |
| Company | Opsonin Pharma Limited |
Drug Package Details
| Strength | 50 mg |
| Storage Condition | |
| Origin Country | Bangladesh |
| Commercial Pack | 50 |
| Price per pack | ৳ 301.00 |
| Cost per pack | ৳ 264.88 |
| Package unit | 10 tabs strip |
| Price per unit | ৳ 6.02 |
| Cost per unit | ৳ 5.30 |
| Discount | 0 |
| Coupon | |
| Remarks |
Sertraline
Sertraline is an antidepressants from the class selective serotonin reuptake inhibitors. Sertraline potentiates serotonergic activity in the central nervous system through inhibition of neuronal reuptake of serotonin (5-HT).
Sertraline is a selective serotonin reuptake inhibitor (SSRI) indicated for the treatment of:
- Major depressive disorder (MDD)
- Obsessive-compulsive disorder (OCD)
- Panic disorder (PD)
- Post-traumatic stress disorder (PTSD)
- Social anxiety disorder (SAD)
- Premenstrual dysphoric disorder (PMDD)
The recommended initial dosage and maximum sertraline dosage in patients with MDD, OCD, PD, PTSD, and SAD are shown in Table-
| Indication | Starting Dose | Therapeutic Range |
| Adults | ||
| MDD | 50 mg | 50-200 mg |
| OCD | 50 mg | |
| PD, PTSD, SAD | 25 mg | |
| Pediatric Patients | ||
| OCD (ages 6-12 years old) | 25 mg | 50-200 mg |
| OCD (ages 13-17 years old) | 50 mg | |
Most common adverse reactions were
- nausea
- diarrhea
- tremor
- dyspepsia
- decreased appetite
- hyperhidrosis
- ejaculation failure
- decreased libido
- Serotonin Syndrome: Risk increases when combined with other serotonergic agents (e.g., SSRI, SNRI, triptans), also when used alone. If this happens, stop taking Sertraline and start receiving supportive care.
- Concurrent use of aspirin, nonsteroidal antiinflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase the risk of bleeding.
- Mania/Hypomania Activation: Screen patients for bipolar disorder.
In patients with seizure disorders, use with caution. - Angle Closure Glaucoma: Antidepressants, including Sertraline, should be avoided in patients with untreated anatomically narrow angles.
Contraindication
Sertraline is contraindicated in-
- Known hypersensitivity to sertraline or excipients
- Concomitant use of pimozide
- Sertraline oral solution only: Concomitant use with
None known.
None known.
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