• Suxamethonium chloride Injection is an ultra-short acting, depolarising, neuromuscular blocking agent. It is used in anaesthesia as a skeletal muscle relaxant to facilitate tracheal intubation and mechanical ventilation surgical procedures.
• Suxamethonium chloride injection is also used to reduce the intensity of muscular contractions associated with pharmacologically or electrically-induced convulsions.

Tracheal Intubation

• The dosage of Suxamethonium Chloride should be individualized based on the patient's age, weight, and clinical condition.
• The medication is administered intravenously and should be given by a trained healthcare professional.
• The recommended initial dose for adults is typically 1 to 1.5 mg/kg, with a maximum dose of 150 mg. Repeat doses may be required to maintain muscle relaxation during prolonged procedures.

Adverse reactions to Suxamethonium Chloride may occur and can include:

• Fasciculations (brief, involuntary muscle twitches)
• Muscle pain or soreness
• Hyperkalemia (high potassium levels in the blood)
• Transient increase in intraocular pressure (rare)
• Transient increase in intragastric pressure (rare)
• Bradycardia (slow heart rate)
• Malignant hyperthermia (rare but potentially life-threatening reaction)

Muscle Pain

Hyperkalemia (High Potassium)

Bradycardia

Hyperthermia (High Body Temperature)

• Suxamethonium Chloride should only be administered by healthcare professionals trained in the use of neuromuscular blockers and airway management.
• The medication should be used with caution in patients with a history of malignant hyperthermia, muscle disorders, or electrolyte imbalances.
• Suxamethonium Chloride can cause a rapid and profound decrease in respiratory function, necessitating mechanical ventilation. Adequate ventilation and oxygenation must be ensured during its use.
• Hyperkalemia, a potentially serious adverse reaction, may occur, particularly in patients with burns, trauma, denervation, or certain neuromuscular disorders.
• Malignant hyperthermia, characterized by hypermetabolism and elevated body temperature, is a rare but potentially fatal reaction to Suxamethonium Chloride. Immediate treatment, including discontinuation of the drug, should be initiated if malignant hyperthermia is suspected.