• Thiopentone Sodium is indicated for the induction of general anesthesia and for the control of intracranial pressure in certain situations.
• It is commonly used for the induction of anesthesia prior to surgery or medical procedures.

Anesthesia

• The dosage of Thiopentone Sodium should be determined by a healthcare professional based on factors such as the patient's age, weight, and individual response.
• It is typically administered intravenously as a slow injection or infusion.
• The dosage and rate of administration should be adjusted according to the desired level of anesthesia and the patient's response.

The most common adverse reactions reported with Thiopentone Sodium include:

• Respiratory depression, including hypoventilation and apnea
• Hypotension (low blood pressure) and cardiovascular depression
• Injection site reactions, such as pain or inflammation
• Nausea and vomiting
• Transient local irritation or burning sensation during injection

Respiratory Depression

Hypotension (Low Blood Pressure)

Nausea

Burning at injection site

• KEEP RESUSCITATIVE AND ENDOTRACHEAL INTUBATION EQUIPMENT AND OXYGEN READILY AVAILABLE. MAINTAIN PATENCY OF THE AIRWAY AT ALL TIMES.
• Respiratory depression: Thiopentone Sodium is a potent respiratory depressant and should be used with caution in patients with compromised respiratory function, such as those with respiratory insufficiency or respiratory tract obstruction.
• Hypotension and cardiovascular effects: Use with caution in patients with cardiovascular disease, as Thiopentone Sodium may cause hypotension, myocardial depression, and cardiac arrhythmias.
• Intravenous use: Thiopentone Sodium should only be administered intravenously and by trained healthcare professionals familiar with the drug's actions, dosing, and administration techniques.
• Monitoring: Patients receiving Thiopentone Sodium should be closely monitored for vital signs, respiratory function, and cardiac status during administration and in the immediate post-anesthetic period.
• Concomitant use of other depressants: Use with caution when administering Thiopentone Sodium with other central nervous system depressants, such as opioids, benzodiazepines, or alcohol, as it may potentiate the sedative effects.