Name Sulphanilamide
Classes Antiinfective Agent
Antibiotic
Sulfonamide
Diseases Genito-Urinary Disease
Vaginal Infection

Sulphanilamide

Sulphanilamide is a veterinary drug belonging to the class of sulfonamides, which are antimicrobial agents. Sulphanilamide works by inhibiting the synthesis of folic acid in bacteria, which is essential for their growth and reproduction. By interfering with folic acid production, Sulphanilamide effectively suppresses bacterial growth and helps to treat or prevent bacterial infections in animals.

 

Sulphanilamide is indicated for use in veterinary medicine for the treatment and prevention of bacterial infections in animals, including:

  • It is applied topically as a powder to treat wounds.
  • Furthermore, it is effective in treating infections caused by microorganisms sensitive to sulfonamides, particularly streptococcal septicaemia, equine pneumonia from streptococci, strangles, joint-ill, and metritis in mares, cows, and ewes.

 

  • The dosage and administration of Sulphanilamide may vary depending on the species, weight, and condition of the animal, as well as the severity of the infection. It is typically administered orally or as an injectable solution.
  • It is important to follow the recommended dosages and treatment schedules provided by the veterinarian.

Adverse reactions to Sulphanilamide are possible and may include:

  • Hypersensitivity reactions (e.g., rash, itching, swelling).
  • Gastrointestinal upset (e.g., vomiting, diarrhea).
  • Rarely, more severe reactions such as blood disorders or liver toxicity may occur.
  • Use Sulphanilamide cautiously in animals with a known hypersensitivity or allergy to sulfonamides.
  • Ensure adequate water intake during treatment to prevent crystalluria and kidney damage, as Sulphanilamide can be concentrated in the urine.
  • Avoid using Sulphanilamide in pregnant or lactating animals unless deemed necessary by the veterinarian.

Contraindication

  • Sulphanilamide is contraindicated in animals with a history of severe hypersensitivity reactions to sulfa drugs.

It is not recommended for use in animals with severe liver or kidney dysfunction, as it may exacerbate these conditions.