Name Tenoxicam
Classes Analgesic / Pain Killer
Central Nervous System Agent
NSAID
Diseases Ankylosing Spondylitis
Arthritis
Bursitis
Inflammatory Disease
Tendonitis

Tenoxicam

Tenoxicam is an oxicam-class nonsteroidal anti-inflammatory drug used to treat the symptoms of painful inflammatory disorders such as arthritis. Tenoxicam acts by inhibiting the formation of endogenous prostaglandins, which play a role in pain, stiffness, tenderness, and edema mitigation.

Tenoxicam is indicated:
• For relief of the signs and symptoms of osteoarthritis.
• For relief of the signs and symptoms of rheumatoid arthritis.

  • Adult: 20 mg as a single dose, taken at the same time each day.
    • Treatment duration: Up to 7 days for acute musculoskeletal disorders and up to 14 days for severe cases.
  • Elderly: Use the lowest effective dose for the shortest possible duration.

Commonly associated side effects include-

  • Edema
  • Anorexia
  • Abdominal pain
  • Constipation
  • Diarrhea
  • Dyspepsia
  • Liver problems
  • Anemia
  • Rash
  • Tinnitus
  • NSAIDs may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with duration of use. Patients with cardiovascular disease or risk factors for cardiovascular disease may be at greater risk
  • TENOXICAM cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency.
  • The pharmacological activity of TENOXICAM in reducing fever and inflammation may diminish the utility of these diagnostic signs in detecting complications of presumed noninfectious, painful conditions.
  • Borderline elevations of one or more liver tests may occur in up to 15% of patients taking NSAIDs, including TENOXICAM.
  • Because of reports of adverse eye findings with nonsteroidal anti-inflammatory agents, it is recommended that patients who develop visual complaints during treatment with TENOXICAM have ophthalmic evaluations.
  • Since cross-reactivity, including bronchospasm, between aspirin and other nonsteroidal anti-inflammatory drugs has been reported in such aspirin-sensitive patients, TENOXICAM should not be administered to patients with this form of aspirin sensitivity and should be used with caution in patients with preexisting asthma.
  • NSAIDs including TENOXICAM cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal.

Contraindication

TENOXICAM is contraindicated in patients with known hypersensitivity to TENOXICAM or other oxicams, such as-

  • TENOXICAM should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.  Severe, rarely fatal, anaphylactic-like reactions to NSAIDs have been reported in such patients .
  • TENOXICAM is contraindicated for the treatment of peri-operative pain in the setting of coronary artery
    bypass graft (CABG) surgery.