Name Terbutaline Sulphate
Classes Respiratory Agent
Bronchodilator
Tocolytic Agent
Diseases Asthma
Bronchitis
Broncho Spasm
Emphysema
Respiratory Disease

Terbutaline Sulphate

Terbutaline Sulphate is a selective beta-2-adrenergic agonist bronchodilator. It relaxes the smooth muscles of the bronchial tubes, uterus, and vascular system by binding to beta-2-adrenergic receptors, thereby increasing the levels of cyclic adenosine monophosphate (cAMP).

 

Terbutaline Sulphate is used for the treatment of bronchial asthma, bronchitis, emphysema, and reversible bronchospasm associated with bronchitis and emphysema. It is also used for the management of premature labor.

 

The dosage of Terbutaline Sulphate depends on the age, weight, and condition of the patient. For adults with asthma, the usual dose is 0.5 mg to 5 mg administered orally or by inhalation every 4 to 6 hours, as needed. For children, the dose is based on their age and weight. The dose for the treatment of premature labor is 2.5 mg administered subcutaneously every 4 hours, up to a maximum of 4 doses.

 

Adverse reactions to Terbutaline Sulphate may include-

  • nervousness
  • tremor
  • headache
  • palpitations
  • tachycardia
  • increased blood pressure
  • flushing
  • sweating
  • nausea

 

  • Terbutaline Sulphate should be used with caution in patients with cardiovascular disorders, such as hypertension, arrhythmias, or coronary artery disease.
  • It should also be used with caution in patients with diabetes, hyperthyroidism, or seizure disorders.
  • Terbutaline Sulphate may interact with other drugs, including beta-blockers, and should not be used concomitantly with these drugs.
  • The drug should also be used with caution during pregnancy and lactation.

 

Contraindication

Terbutaline Sulphate is contraindicated in patients with hypersensitivity to the drug or its components. 

 

Terbutaline Sulphate should also not be used in patients with uncontrolled hypertension or cardiac arrhythmias.