| Name | Timolol |
| Classes |
Cardiovascular Agent Dermatological/Topical Agent Ophthalmic Preparation Antihypertensive Beta-Adrenoceptor Blocker Glaucoma Agent |
| Diseases |
Glaucoma Ophthalmic Disease |
Bangla
EnglishTimolol
Timolol is a beta-adrenergic receptor blocker that is non-selective. It has no intrinsic sympathomimetic activity, no direct myocardial depressive activity, and no local anesthetic activity.
Timolol is indicated for Glaucoma
Eye drops Solution: Instill 1 drop of 0.25 percent solution bid into the affected eye(s) at first; if response is inadequate, raise to 1 drop of 0.5 percent solution bid; if controlled, reduce to 1 drop once daily. 1 drop bid of 0.5 percent solution is not to be exceeded.
Gel-forming eye drops: 0.25% or 0.5% Gel-forming eye drops: Instill 1 drop into the affected eye(s) once a day.
How to administer eye drops:
Commonly associated side effects include-
- Eye burning
- Bradycardia
- hypotension
- arrhythmia
- Raynaud's phenomenon
- headache
- dizziness
- asthenia
- abdominal discomfort
- nausea
- Caution should be exercised while treating patients with-
- poor cardiac function
- diabetes mellitus
- myasthenia gravis
- cerebrovascular insufficiency
- atopy.
- Avoid sudden withdrawal since it can worsen angina symptoms or cause a heart attack in people with coronary artery disease, or trigger a thyroid crisis in thyrotoxicosis patients.
- Caution should be taken for those who are receiving significant surgery.
- Hyperthyroidism and hypoglycemia symptoms may be masked. Angle-closure glaucoma should not be treated with ophthalmic solution alone.
Contraindication
Timolol is contraindicated in patients hypersensitive to timolol or any component of the product.
Timolol is contraindicated in patients with-
- bronchial asthma
- severe chronic obstructive pulmonary disease
- sinus bradycardia
- second or third degree atrioventricular block
- overt cardiac failure
- cardiogenic shock
