Timolol maleate is indicated in adults for-

• Ocular hypertension
• Chronic open-angle glaucoma
• Secondary glaucoma

Glaucoma

Occular hypertension

• Recommended therapy is one drop of 2.5 mg/ml solution in the affected eye, once or twice (morning and evening) a day.
• If clinical response is not adequate, dose may be changed to one drop of 5 mg/ml solution in each affected eye, once or twice (morning and evening) a day. If needed, Timolol maleate may be used with other agent(s) for lowering intra-ocular pressure. The use of two topical beta-adrenergic blocking agents is not recommended
• Intra-ocular pressure should be reassessed approximately four weeks after starting treatment because response to timolol maleate may take a few weeks to stabilize.

How to apply eye drops:

Eye Drops

Commonly associated side effects include-

• Eye burning
• Bradycardia
• hypotension
• arrhythmia
• Raynaud's phenomenon
• headache
• dizziness
• asthenia
• abdominal discomfort
• nausea

Ocular burning/ Eye burning	Bradycardia	Hypotension
Arrhythmia	Headache	Dizziness

• Caution should be exercised while treating patients with-
  • poor cardiac function
  • diabetes mellitus
  • myasthenia gravis
  • cerebrovascular insufficiency
  • atopy.
• Avoid sudden withdrawal since it can worsen angina symptoms or cause a heart attack in people with coronary artery disease, or trigger a thyroid crisis in thyrotoxicosis patients.
• Caution should be taken for those who are receiving significant surgery.
• Hyperthyroidism and hypoglycemia symptoms may be masked. Angle-closure glaucoma should not be treated with ophthalmic solution alone.