Name Bimatoprost
Classes Dermatological/Topical Agent
Ophthalmic Preparation
Glaucoma Agent
Diseases Glaucoma
Ophthalmic Disease
Reduced Eyelash

Bimatoprost

Bimatoprost is a prostaglandin analogue. It is a selective FP prostanoid receptor agonist which is believed to reduce intraocular pressure by increasing uveoscleral outflow.

Bimatoprost is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. 

  • Open angle glaucoma
  • Ocular hypertension

One drop in the affected eye(s) once daily in the evening.

Bimatoprost may cause the following side effects-

  • ocular hyperemia 
  • decreased visual acuity
  • eye discomfort
  • foreign body sensation
  • pain
  • pruritus
  • abnormal vision
  • blepharitis
  • blurred vision
  • cataract
  • conjunctivitis
  • corneal staining
  • dry eye
  • iris discoloration
  • keratitis
  • lid margin crusting
  • ocular inflammation
  • photophobia
  • subconjunctival hemorrhage and tearing
  • Pigmentation: Pigmentation of the iris, periorbital tissue (eyelid) and eyelashes can occur. Iris pigmentation likely to be permanent. 
  • Eyelash Changes: Gradual change to eyelashes including increased length, thickness and number of lashes. It is usually reversible. 
  • Bimatoprost should be used with caution in patients with active intraocular inflammation (e.g., uveitis) because the inflammation may be exacerbated. 
  • Macular edema, including cystoid macular edema, has been reported during treatment with Bimatoprost ophthalmic 
  • Bimatoprost has not been evaluated for the treatment of angle-closure, inflammatory or neovascular glaucoma. 
  • Contact lenses should be removed prior to instillation of Bimatoprost and may be reinserted 15 minutes following its administration. 
  • Bacterial keratitis has been linked to the use of multiple-dose containers of topical ophthalmic products. These containers had been contaminated inadvertently by patients, the majority of whom had a concurrent corneal disease or a disruption of the ocular epithelial surface.

Contraindication