Name Tulobuterol Hydrochloride
Classes Respiratory Agent
Antiasthmatic
Diseases Broncho Spasm
Respiratory Disease

Tulobuterol Hydrochloride

Tolubuterol Hydrochloride is beta 2 adrenergic receptor agonist. Beta 2 receptors are predominantly located in the trachea and air ways. Activation of the receptor causes relaxation of smooth muscles which causes bronchodialation.

Tolubuterol Hydrochloride is indicated in-

  • Asthma
  • Bronchospasm
  • COPD
  • Exercise-Induced Bronchospasm Prevention

Oral
Bronchodilator

Adult: Initially, 1-2 mg twice a day, increase to 2 mg thrice a day if necessary.
Child: 1-6 yr: 0.25-0.5 mg twice a day, 6-10 yr: 0.5-1 mg twice a day, 10-14 yr: 1-1.5 mg twice a day.
 
Transdermal
Chronic obstructive pulmonary disease
Adult: 2 mg as transdermal patch once daily. To be used with anti-inflammatory therapy.
 

Side effects include-

  • Fine tremor of skeletal muscle
  • palpitations
  • muscle cramps
  • tachycardia
  • tension
  • headache
  • edema
  • hypersensitivity reactions

Special precautions should be taken in-

  • Hyperthyroidism
  • myocardial insufficiency
  • arrhythmias
  • QT-interval prolongation
  • hypertension
  • Diabetes mellitus

 

Contraindication

Contraindicated in patients hypersensitive to any component of the medication.

Contraindicated in Pheochromocytoma.