Name Urea
Classes Dermatological/Topical Agent
Emollient / Moisturising Agent
Diseases Cracking
Roughness
Skin Disorder

Urea

Urea, classified as a keratolytic and emollient, is utilized in dermatology for its hydrating and exfoliating properties. It functions by softening and moisturizing the skin, promoting the shedding of dead skin cells, and enhancing skin barrier function.

Urea is indicated for:

  • Dry Skin Conditions: Used to alleviate dryness and flakiness of the skin.
  • Hyperkeratotic Conditions: Beneficial in treating conditions characterized by excessive skin thickening, such as calluses and corns.
  • Ichthyosis: Employed to manage and improve the symptoms of ichthyosis, a group of skin disorders causing dry, scaly skin.

Dosage recommendations may vary based on the specific dermatological condition and patient age.

  1. Dry Skin Conditions:

    • Adults: Apply a thin layer of urea cream or lotion to the affected areas as needed.
    • Pediatric Patients: Dosage should be determined by a healthcare professional based on the child's age and condition.
  2. Hyperkeratotic Conditions:

    • Adults: Apply a generous amount of urea cream to affected areas, covering with a bandage if directed by a healthcare provider.
    • Pediatric Patients: Dosage should be determined by a healthcare professional based on the child's age and condition.
  3. Ichthyosis:

    • Adults and Pediatric Patients: Apply urea cream to affected areas as directed by a healthcare professional, usually once or twice daily.

Adverse reactions associated with urea are listed from most common to least common:

  • Localized irritation
  • Stinging or burning sensation
  • Allergic skin reactions, such as rash or itching
  • Avoid Eye Contact: Keep urea-containing products away from the eyes and mucous membranes.
  • External Use Only: Urea is for external use only; avoid ingestion.
  • Skin Sensitivity: Discontinue use if excessive irritation or allergic reactions occur.
  • Pediatric Use: Use in pediatric patients should be supervised by a healthcare professional.

Contraindication

Urea is contraindicated in individuals with known hypersensitivity to urea or any of its components.