Name Vitamin B12
Classes Nutritional Supplement
Vitamin
Diseases Malnutrition
Pernicious Anaemia
Vitamin B12 Deficiency

Vitamin B12

Vitamin B12 is required for the proper function and development of almost all the organ systems, including the brain, nerves, and blood cells. Methylcobalamin is the active form of vitamin B12. The most common type used in supplements is cyanocobalamin, which is metabolized by the body into the active form.

Vitamin B12 is indicated for the following conditions-

  • Malnutrition
  • Vitamin B12 deficiency
  • Cataracts
  • Cankers
  • Fatigue
  • Cyanide poisoning
  • Macrocytic anemia
  • Thyrotoxicosis
  • Malignancy

 

The adult dose for vitamin B12 differs from person to person depending upon the condition being treated. The usual dose as a supplement is 25 to 2000 mcg orally daily. The usual pediatric dose for vitamin B12 deficiency is 0.5 to 3 microgram daily,

 

The commonly associated side effects include-

  • Arthralgia
  • Dizziness
  • Headache
  • Pharyngitis
  • Diarrhea
  • Dyspepsia

After receiving a coronary stent, avoid using a combination of vitamin B12, folate, and vitamin B6. This combination may raise the likelihood of blood vessel narrowing. Intensive treatment of B12-deficient megaloblastic anemia may result in hypokalemia and death. In patients with optic nerve atrophy, use with caution. Treatment of severe vitamin B12 megaloblastic anemia may result in thrombocytosis.

Contraindication

Contraindicated in patients hypersensitive to any component of the preparation.

Contraindicated in-

  • Leber's Disease
  • Tobacco amblyopia