Name Brimonidine Tartrate
Classes
Diseases Glaucoma
Ophthalmic Disease

Brimonidine Tartrate

Brimonidine Tartrate is a medication used to lower intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. Brimonidine tartrate works by reducing the production of aqueous humor, and by increasing the outflow of aqueous humor through the trabecular meshwork. The drug achieves this by acting on alpha-2 adrenergic receptors in the eye, causing vasoconstriction and reducing aqueous humor production.

 

Brimonidine Tartrate is indicated for the treatment of glaucoma-

 

One drop in the affected eye(s), three times daily, approximately 8 hours apart.

 

The most common adverse reactions with brimonidine tartrate are-

  • ocular burning or itching
  • blurred vision
  • conjunctival hyperemia
  • eye irritation

Other adverse reactions may include dry mouth, headache, and drowsiness.

 

  • Brimonidine tartrate may cause decreased heart rate and blood pressure. Patients with severe cardiovascular disease, cerebrovascular disease, or chronic obstructive pulmonary disease may be at increased risk for adverse events.
  • Brimonidine tartrate may cause drowsiness, fatigue, or confusion. Patients should use caution when performing activities that require mental alertness, such as operating a vehicle or heavy machinery.
  • Brimonidine tartrate may cause a rebound increase in IOP when the medication is discontinued.

 

Contraindication

Contraindicated in Patients with known hypersensitivity to brimonidine tartrate or any of its components.

 

Brimonidine is contraindicated in neonates and infants.