Name | Chlorpheniramine Maleate + Dexamethasone |
Classes |
Dermatological/Topical Agent Respiratory Agent Ophthalmic Preparation Antiallergic Agent |
Diseases |
Allergic Reaction Coughing Runny Nose Sneezing Watery Eye |
Chlorpheniramine Maleate + Dexamethasone
Chlorpheniramine Maleate + Dexamethasone is a combination drug that belongs to the class of antihistamines and corticosteroids. Chlorpheniramine Maleate works by blocking the action of histamine, a chemical released by the body that causes allergy symptoms such as sneezing, runny nose, and watery eyes. Dexamethasone is a steroid that helps to reduce inflammation and swelling.
This drug combination is indicated for the treatment of-
- seasonal and perennial allergic rhinitis
- acute and chronic dermatitis
- contact dermatitis
- atopic dermatitis
- insect bite reactions
The dosage of Chlorpheniramine Maleate + Dexamethasone depends on the patient's age, weight, and medical condition. It is usually given as a tablet or syrup, taken orally, with or without food. The following are the recommended dosages for different age groups:
- Adults and children over 12 years old: 1-2 tablets or 5-10 mL of syrup every 4-6 hours, not to exceed 12 tablets or 60 mL in a 24-hour period.
- Children aged 6-12 years: 0.5-1 tablet or 2.5-5 mL of syrup every 4-6 hours, not to exceed 6 tablets or 30 mL in a 24-hour period.
- Children aged 2-6 years: 0.25-0.5 tablet or 1.25-2.5 mL of syrup every 4-6 hours, not to exceed 3 tablets or 15 mL in a 24-hour period.
The most common adverse reactions of Chlorpheniramine Maleate + Dexamethasone include-
- drowsiness
- dizziness
- dry mouth
- blurred vision
- nausea and vomiting
- This drug combination may cause drowsiness or dizziness, which can impair the patient's ability to operate machinery or drive a car.
- Patients with glaucoma, enlarged prostate, bladder obstruction, or other urinary problems should use this drug combination with caution.
- Patients with liver or kidney disease may require dosage adjustments or close monitoring while taking this medication.
- Long-term use of corticosteroids like Dexamethasone may increase the risk of osteoporosis, cataracts, and adrenal suppression.
- This drug combination may interact with other medications, including other antihistamines, sedatives, tranquilizers, and monoamine oxidase inhibitors (MAOIs).
- Patients should avoid drinking alcohol while taking this medication as it may increase drowsiness and dizziness.
Contraindication
Chlorpheniramine Maleate + Dexamethasone is contraindicated in patients who have a known hypersensitivity to any of its components.
None known.
Chlorpheniramine Maleate + Dexamethasone is contraindicated in patients as well as in patients with systemic fungal or bacterial infections.