Name Calcium Acetate
Classes Electrolyte and Mineral
Nutritional Supplement
Phosphate Binder
Diseases Bone Fracture
Kidney Disease
Kidney Failure

Calcium Acetate

Calcium Acetate is a calcium salt of acetic acid. It is soluble in the plasma and is converted into Ca2+ ions. As a result it can act as a phosphate binder and as calcium supplement.

Calcium acetate is indicated in-

  • Hyperphosphatemia
  • Hypocalcemia
  • Starting dose is 2 gelcaps with each meal. 
  • Titrate the dose every 2-3 weeks until acceptable serum phosphorus level is reached. Most patients require 3-4 gelcaps with each meal.

The most common side effects are-

  • Hypercalcemia
  • Nausea
  • Vomiting
  • Dizziness
  • Edema
  • Weakness
  • Hypercalcemia may aggravate digitalis toxicity. 
  • Chronic hypercalcemia may lead to vascular calcification and other soft-tissue calcification. 
  • When patients with end-stage renal disease are given calcium, including calcium acetate, they may develop hypercalcemia. Calcium supplements, particularly calcium-based nonprescription antacids, should not be taken at the same time as Calcium acetate.

Contraindication

Contraindicated in patients hypersensitive to any component of the formulation.