NameCeftibuten
Classes Anti-infective Agent
Antibiotic
Cephalosporine
Diseases Bronchitis
Gastroenteritis
Gonorrhea
Infectious Disease
Otitis
Pneumonia
Sinusitis
Tonsillitis
Urethritis

Ceftibuten

Ceftibuten is a 3rd gen cephalosporin that kills bacteria by inhibiting cell wall synthesis. It is a broad spectrum antibiotic.

Ceftibuten is used to treat the following infections-

  • Acute Bacterial Exacerbations of Chronic Bronchitis
  • Otitis Media
  • Pharyngitis
  • Tonsillitis
  • Ceftibuten is available as capsule and powder for suspension.
  • The usual adult dose for ceftibuten is 400mg per day. The dosage should be divided into 4 individual doses. The treatment usually lasts for up to 10 days.
  • For paediatric patients, the recommended dose is 9mg/kg.
  • Dosage adjustment is required for renally impaired patients.

How to reconstitute powder for suspension:

Side effects commonly associated with ceftibuten include-

  • Nausea
  • Headache
  • Diarrhea
  • Dyspepsia
  • Dizziness
  • Abdominal pain
  • Vomiting
  • Ceftibuten should be used with caution in people who have had gastrointestinal disorders, especially colitis.
  • Diarrhoea, especially if severe and/or chronic, and occurring during or shortly after therapy, could be a sign of Clostridium difficile-associated illness (CDAD). CDAD can range in severity from minor to life-threatening, with pseudomembranous colitis being the most severe.

Contraindication

Ceftibuten is contraindicated in patients hypersensitive to beta lactam antibiotics, such as-