Choline is indicated for the treatment of choline deficiency and for supplementation in certain medical conditions, such as liver disease and pregnancy. It is also used as a nootropic agent to enhance cognitive function, and as a performance enhancer in athletes.

Malnutrition

The dosage of choline varies depending on the patient's age, medical condition, and other factors. The recommended daily intake of choline for adults is 1-3 gm per day. The dosage for children and infants is typically lower and should be determined by a healthcare professional.

Choline is generally well-tolerated and safe when taken within the recommended doses. However, high doses of choline may cause adverse effects, such as gastrointestinal distress, diarrhea, nausea, vomiting, and a fishy odor of the body secretions.

Diarrhea

Nausea

Vomiting

• Choline supplements should be used with caution in patients with kidney or liver disease, as they may be at risk of developing adverse effects.
• Choline supplements should not be used in patients with a history of bipolar disorder, as it may worsen the symptoms.
• Patients with a history of asthma may be at increased risk of developing respiratory distress when taking choline supplements.
• Choline supplements may interact with certain medications, such as anticholinergic drugs, which may lead to adverse effects.