Name Cyanocobalamin
Classes Nutritional Supplement
Vitamin
Diseases Malnutrition
Vitamin B Complex Deficiency

Cyanocobalamin

Cyanocobalamin is a synthetic form of Vitamin B12, which is a water-soluble vitamin. It plays an essential role in DNA synthesis, neurological function, and red blood cell formation.

 

Cyanocobalamin is used to treat Vitamin B12 deficiency caused by malabsorption or other medical conditions that lead to a decreased intake or absorption of Vitamin B12, such as pernicious anemia, gastrointestinal pathology, or surgical removal of the stomach. It is also used as a dietary supplement in people with a low intake of Vitamin B12.

 

The dosage and administration of Cyanocobalamin depend on the patient's age, medical condition, and response to treatment. The recommended daily dose of Cyanocobalamin for adults is 2.4 micrograms. The dose may be higher for pregnant or breastfeeding women, individuals with malabsorption syndromes, or for the treatment of Vitamin B12 deficiency. Cyanocobalamin is usually administered intramuscularly or subcutaneously, but it can also be taken orally.

 

The following adverse reactions have been reported with the use of Cyanocobalamin:

  • Injection site reactions such as pain, redness, and swelling
  • Dizziness, headache, and nervousness
  • Nausea, vomiting, and diarrhea
  • Itching, rash, and hives
  • Serious allergic reactions such as anaphylaxis, which can cause difficulty breathing, chest tightness, and swelling of the face, lips, tongue, or throat

 

The use of Cyanocobalamin may not be appropriate for everyone, and certain precautions should be taken:

  • Individuals with hypersensitivity to Cobalt or Vitamin B12 should not use Cyanocobalamin.
  • Cyanocobalamin should be used with caution in individuals with a history of allergy or sensitivity to any of its components.
  • Cyanocobalamin should be used cautiously in individuals with a history of blood clotting disorders or who are taking anticoagulants.
  • Cyanocobalamin should not be used as a substitute for folic acid in the treatment of pernicious anemia.
  • Cyanocobalamin may interfere with certain laboratory tests, including diagnostic tests for serum folate levels.
  • Cyanocobalamin should not be used during pregnancy unless clearly necessary. It is not known whether Cyanocobalamin is excreted in breast milk.

 

Contraindication

Cyanocobalamin is contraindicated in individuals with hypersensitivity to Cobalt or Vitamin B12.

 

Cyanocobalamine is contraindicated in-

  • Leber's disease
  • Polycythemia vera