| Name | Dapsone |
| Classes |
Dermatological/Topical Agent Topical Antiinfective Agent Antiacne Agent |
| Diseases |
Leprosy Lesions Skin Disorder |
Bangla
EnglishDapsone
Dapsone belongs to the class of antimicrobial agents, specifically a sulfone. Its mechanism of action involves inhibition of dihydropteroate synthase, an enzyme involved in the synthesis of folic acid in microorganisms. This leads to disruption of bacterial and parasitic DNA synthesis, making it effective against certain bacteria and protozoa.
Dapsone Gel is indicated for the topical treatment of acne vulgaris.
- Apply twice daily.
- Apply approximately a pea-sized amount of Dapsone Gel, 5%, in a thin layer to the acne affected area.
- If there is no improvement after 12 weeks, treatment with Dapsone Gel, 5%, should be reassessed.
- For topical use only. Not for oral, ophthalmic, or intravaginal use.
- Methemoglobinemia: Cases of methemoglobinemia have been reported. Discontinue Dapsone gel if signs of methemoglobinemia occur
- Hematologic Effects: Some subjects with G6PD deficiency using Dapsone Gel developed laboratory changes suggestive of hemolysis
Contraindication
None known.
None known.
None known.