Desferrioxamine Mesilate

Name	Desferrioxamine Mesilate
Classes	Antidote
Diseases	Iron Deficiency Toxicity

Back

Bangla

English

Desferrioxamine Mesilate

Desferrioxamine Mesilate is an iron chelator belonging to the class of drugs known as chelating agents. It works by binding to excess iron in the body and forming a stable complex that is excreted in the urine. This helps to reduce the amount of iron that can cause damage to the body's tissues.

Indication and Usage

Desferrioxamine Mesilate is indicated for the treatment of chronic iron overload due to blood transfusions in patients with transfusion-dependent anemias such as beta-thalassemia major and sickle cell disease. It is also used in the treatment of acute iron poisoning.

Iron overload

Dosage & Administration (How to take this medication)

A dose of 1000 mg should be administered initially. This may be followed by 500 mg every 4 hours for two doses. Depending upon the clinical response, subsequent doses of 500 mg may be administered every 4-12 hours. The total amount administered should not exceed 6000 mg in 24 hours.

Side effect

Common side effects of Desferrioxamine Mesilate include-

skin rash
redness, swelling or pain at the injection site
burning at injection site
nausea
vomiting
diarrhea
abdominal pain
headache
dizziness
fever & chills

Skin Rash

Pain at injection site

Diarrhea

Abdominal Pain

Precaution/Good to know

Desferrioxamine Mesilate should be used with caution in patients with renal impairment or hearing loss.
In patients receiving Desferrioxamine Mesilate , rare cases of mucormycosis, some with a fatal outcome, have been reported.
It should not be used in patients with known hypersensitivity to the drug.
Patients should be monitored for signs of anaphylaxis, renal function, hearing, and visual acuity during treatment.
Pregnancy and lactation information is limited, and the drug should only be used if clearly needed.