Desonide is a corticosteroid indicated for the topical treatment of mild to moderate atopic dermatitis in patients 3 months of age and older.

Dermatitis

• Apply as a thin layer to the affected areas two times daily and rub in gently. 
• Therapy should be discontinued when control is achieved. 
• If no improvement is seen within 4 weeks, reassessment of diagnosis may be necessary.
• Should not be used with occlusive dressings. 
• Treatment beyond 4 consecutive weeks is not recommended. 
• For topical use only. Not for oral, ophthalmic, or intravaginal use.

Side effects associated with topical desonide are relatively rare. The following side effects were reported-

• burning
• rash
• pruritus

Burning sensation

Rash

Pruritus

• Topical corticosteroids can suppress the hypothalamic pituitary adrenal (HPA) axis, cause Cushing's syndrome, and reveal latent diabetes.
• Systemic absorption may necessitate testing for HPA axis suppression.
• If HPA axis suppression develops, modify use.
• Corticosteroids with high potency, use on large areas, prolonged use, or occlusive use may increase systemic absorption.
• Local side effects may include atrophy, striae, irritation, acneiform eruptions, hypopigmentation, and allergic contact dermatitis, and are more likely with occlusive use or stronger corticosteroids.
• When given topical corticosteroids, children may be more susceptible to systemic toxicity.