• Flunarizine is indicated for the prophylaxis of migraine headaches.
• It is used to reduce the frequency, severity, and duration of migraine attacks

Migraine

• The dosage of Flunarizine may vary depending on the individual and the severity of migraines.
• The usual recommended starting dose is 5 mg per day, taken at bedtime.
• The healthcare provider may adjust the dosage based on the patient's response and tolerability.
• It is important to follow the prescribed dosage and administration instructions provided by the healthcare provider.

The following side effects may occur with Flunarizine-

• Drowsiness or fatigue.
• Weight gain.
• Dizziness or lightheadedness.
• Dry mouth.
• Depression or mood changes.
• Extrapyramidal symptoms (such as parkinsonism-like symptoms).
• Gastrointestinal disturbances (such as nausea, vomiting, or constipation).
• Tremor or involuntary movements.
• Allergic reactions (rash, itching).

Drowsiness

Dizziness

Dry Mouth

Depression

• Sedation: Flunarizine may cause drowsiness or fatigue. Patients should exercise caution when driving or operating machinery until they know how the medication affects them.
• Depression and suicidal ideation: Flunarizine has been associated with depressive symptoms and, rarely, suicidal ideation. Patients should be closely monitored for changes in mood or behavior and appropriate measures should be taken.
• Movement disorders: Flunarizine may cause extrapyramidal symptoms, including parkinsonism-like symptoms and tremor. Patients with a history of movement disorders should be closely monitored.
• Weight gain: Flunarizine has been associated with weight gain. Patients should be advised about the potential for weight gain and appropriate lifestyle modifications should be considered.
• Cardiovascular effects: Flunarizine may have cardiovascular effects, including prolonged QT interval. It should be used with caution in patients with a history of cardiovascular disease or risk factors.
• Pregnancy and breastfeeding: Flunarizine is not recommended for use during pregnancy or breastfeeding.