Name Pyrantel Pamoate
Classes Antiinfective Agent
Anthelmintic/Antiparasitic
Diseases Infectious Disease
Worm Infection

Pyrantel Pamoate

Pyrantel is an antihelmintic medication. Pyrantel acts as a neuromuscular blocker in parasites. As a results it renders the parasites paralyzed.

 

Pyrantel Pamoate is indicated in the following conditions-

  • Ascariasis (round worm infection)
  • Enterobiasis (pin worm infection)

 

Ascariasis

  • Adult: Doses are expressed as pyrantel pamoate base. Alternative agent: Usual dose: 10-11 mg/kg as a single dose. Max: 1,000 mg/dose.
Enterobiasis
  • Adult: Doses are expressed as pyrantel pamoate base. Usual dose: 10-11 mg/kg as a single dose, repeated after 2 weeks to prevent reinfection. Max: 1,000 mg/dose.
    Child: ≥2 years Same as adult dose.

The following side effects were reported with Pyrantel-

  • Nausea
  • vomiting
  • abdominal pain
  • diarrhoea
  • anorexia

Pyrantel and piperazine should not used concomitantly as the antagonize each other.

 

Contraindication

Contraindicated in patients hypersensitive to pyrantel.