Risedronate is indicated for:

• Treatment and prevention of postmenopausal osteoporosis 
• Treatment to increase bone mass in men with osteoporosis 
• Treatment and prevention of glucocorticoid-induced osteoporosis 
• Treatment of Paget’s disease 

Post Menopausal Osteoporosis (Brittle Bone)

Osteoporosis (Brittle Bone)

Paget's Disease

Risedronate sodium must be taken with plain water (6 to 8 oz) at least 30 minutes before the first food or drink of the day; do not lie down for 30 minutes 

• Treatment of Osteoporosis in Postmenopausal Women: 5 mg daily, 35 mg once a week, 75 mg taken on two consecutive days each month, or 150 mg once a month.
• Prevention of Osteoporosis in Postmenopausal Women: 5 mg daily, or 35 mg once a week.
• Men with Osteoporosis: 35 mg once a week. 
• Treatment and Prevention of Glucocorticoid-Induced Osteoporosis: 5 mg daily.
• Paget’s Disease: 30 mg daily for 2 months.

Most common adverse reactions reported in patients treated with ACTONEL are:

• back pain
• arthralgia
• abdominal pain
• dyspepsia
• generalized rash
• eye inflammation 

Back Pain

Arthralgia

Abdominal Pain

Dyspepsia

• Upper gastrointestinal irritation may occur. Dosing instructions should be followed. Discontinue use if new or worsening symptoms occur. 
• Hypocalcemia may worsen and must be corrected prior to use.
• Osteonecrosis of the jaw has been reported rarely.
• Severe bone, joint, or muscle pain may occur. Consider discontinuing use if severe symptoms develop.
• Before initiating treatment in patients with glucocorticoid-induced osteoporosis, sex steroid hormonal status of both men and women should be ascertained and appropriate replacement considered. 
• Bisphosphonates may interfere with bone-imaging agents.