| Name | Tiotropium |
| Classes |
Respiratory Agent Antiasthmatic Anticholinergic Bronchodilator |
| Diseases |
Bronchitis Chronic Obstructive Pulmonary Disease (COPD) Emphysema Respiratory Disease |
Bangla
EnglishTiotropium
Tiotropium is a long-acting bronchodilator that belongs to the class of anticholinergics. It works by blocking the action of acetylcholine, a neurotransmitter, on the smooth muscles of the airways, leading to relaxation and dilation of the bronchial passages.
Tiotropium is indicated for the maintenance treatment of-
- chronic obstructive pulmonary disease (COPD)
- chronic bronchitis
- emphysema
Tiotropium is administered via inhalation and is available as a dry powder inhaler (DPI) or as a solution for use with a nebulizer. The recommended dosage of tiotropium is one inhalation of the DPI or nebulizer solution (equivalent to 18 mcg of tiotropium) once daily, at the same time each day.
Most common adverse reactions were-
- Bronchitis
- COPD exacerbation
- Dyspnea/ shortness of breath
- Headache
- Dizziness
- Dry mouth
- Sinusitis
- Tiotropium is not indicated for the treatment of acute bronchospasm or asthma.
- Tiotropium should be used with caution in patients with narrow-angle glaucoma, as it may increase intraocular pressure.
- Tiotropium should be used with caution in patients with urinary retention or bladder-neck obstruction.
- Tiotropium should be used with caution in patients with a history of hypersensitivity reactions to atropine or other anticholinergics.
- Tiotropium should not be used in patients with a known hypersensitivity to tiotropium or any of its components.
Contraindication
- Contraindicated in patients with hypersensitivity to Tiotropium or any component of the medication.
- Contraindicated in patients with hypersensitivity to atropine or atropine derivatives-
None known.
None known.