Ethinylestradiol + Levo Norgestrel is a contraceptive used to prevent pregnancy.

Prevention of Pregnancy

• Take LNG/EE Tablets in one of two ways:
• • swallow whole on an empty stomach or
  • chew and then immediately swallow with a full glass of 240 mL water on an empty stomach.
  • Start on Day 1 and take each tablet at the same time every day in the order directed on the blister pack, or 
  • Start on a Sunday and take each tablet at the same time every day in the order directed on the blister pack.
• Take one tablet daily for 28 consecutive days: one white active tablet daily during the first 21 consecutive days, followed by one peach inactive tablet daily during the 7 following days. 

Common adverse reactions are:

• headache
• abdominal pain
• nausea
• metrorrhagia
• vaginal moniliasis and pain
• acne
• vaginitis

Headache

Abdominal Pain

Nausea

Vaginitis

• Levonorgestrel and Ethinyl Estradiol (LNG/EE) Tablets is contraindicated in women over 35 years old who smoke.
• Cigarette smoking increases the risk of serious cardiovascular side effects from combination hormonal contraceptive (CHC) use
• Vascular risks: Stop if a thrombotic or thromboembolic event occurs. Stop LNG/EE Tablets at least 4 weeks before and through 2 weeks after major surgery. Start no earlier than 4 weeks after delivery, in females who are not breast-feeding. Consider cardiovascular risk factors before initiating in all females, particularly those over 35 years.
• Liver disease: Discontinue LNG/EE Tablets if jaundice occurs. 
• Hypertension: If used in females with well-controlled hypertension, monitor blood pressure. Stop use of Levonorgestrel and Ethinyl Estradiol Tablets if blood pressure rises significantly. 
• Gallbladder disease: May cause or worsen gallbladder disease. 
• Adverse carbohydrate and lipid effect: Monitor glucose in prediabetic and diabetic females using LNG/EE Tablets. Consider an alternate contraceptive method for females with uncontrolled dyslipidemia. 
• Headache: Evaluate significant change in headaches and discontinue LNG/EE Tablets if indicated.
• Uterine bleeding: May cause irregular bleeding or amenorrhea. Evaluate for other causes if symptoms persist