Name Glycerol
Classes Gastrointestinal Agent
Laxatives
Diseases Constipation
Gastrointestinal Disease

Glycerol

Glycerol is a hyperosmotic laxative that draws water into the colon, which stimulates bowel movement. It belongs to the class of laxatives known as osmotic laxatives.

Glycerol is used to relieve constipation or to empty the bowels before medical procedures such as colonoscopy. It can also be used to treat fecal impaction.

  • Adults: One suppository (2 g) inserted rectally as needed, up to a maximum of three suppositories per day.
  • Children 2-5 years old: Half of one suppository (1 g) inserted rectally as needed, up to a maximum of one and a half suppositories per day.
  • Children 6-12 years old: One suppository (2 g) inserted rectally as needed, up to a maximum of two suppositories per day.

The following side effects may appear with the use of glycerol:

  • Rectal irritation or discomfort
  • Mild cramps or abdominal pain
  • Diarrhea
  • Nausea
  • Headache
  • Glycerol should not be used for more than one week without consulting a healthcare provider.
  • Do not use Glycerol if you are allergic to it or any of its ingredients.
  • If you have a medical condition such as inflammatory bowel disease or heart disease, consult your healthcare provider before using Glycerol.
  • Glycerol may interact with certain medications such as diuretics or blood pressure medications, so be sure to inform your healthcare provider of all medications you are taking.
  • Avoid using Glycerol if you are experiencing abdominal pain, nausea, or vomiting, as these could be symptoms of a more serious condition.

Contraindication

Glycerol is contraindicated in individuals with a known hypersensitivity to glycerine or any of its ingredients.

Glycerol should not be used by individuals with a history of bowel obstruction, perforation, or severe inflammatory conditions of the bowel.