Indapamide is indicated for the treatment of hypertension, alone or in combination with other antihypertensive agents. It may also be used in the management of edema associated with congestive heart failure, hepatic cirrhosis, and renal disease.

Hypertension (High Blood Pressure)

Edema

• The usual recommended starting dose of indapamide for hypertension is 1.25 mg once daily, taken in the morning. The dose may be increased to 2.5 mg once daily, depending on the patient's response to treatment. The maximum daily dose is 5 mg.
• The adult starting indapamide dose for edema of congestive heart failure is 2.5 mg as a single daily dose taken in the morning. If the response to 2.5 mg is not satisfactory after one week, the daily dose may be increased to 5.0 mg taken once daily. 

Side effects associated with Indapamide may include-

• Headache
• Pain
• Dizziness
• Rhinitis
• Hyperuricemia
• Hyperglycemia
• Hypertriglyceridemia
• Infection

Headache

Dizziness

Hyperuricemia

Infection

• Indapamide may cause electrolyte imbalances (such as low blood potassium or sodium levels), especially in elderly patients or those with renal impairment. Therefore, serum electrolyte levels should be monitored regularly.
• The drug may also cause hyperuricemia, which may lead to gout attacks in susceptible individuals.
• Indapamide should be used with caution in patients with impaired liver function or diabetes mellitus.
• The drug may cause dizziness, fatigue, or other symptoms that may impair the patient's ability to drive or operate machinery.
• Indapamide should be avoided in patients with a history of sulfonamide allergy or hypersensitivity to any of the drug's components.