Labetalol is indicated for-

• Hypertension
• Angina

Hypertension (Hight Blood Pressure)

Angina

Hypertension and angina:

Starting with 100mg twice a day, the treatment should be gradually increased. This may be sufficient to manage blood pressure in people who are currently taking antihypertensives and who have a low body weight. Increases in dose of 100mg twice daily should be made every two weeks in others. Many patients' blood pressure can be stabilized with 200mg twice daily, and up to 800mg twice daily may be provided. Daily dosages of up to 2400mg have been given to patients with severe, resistant hypertension. These doses should be divided into three or four daily doses.

Commonly associated side effects include-

• dizziness
• headache
• bradycardia
• orthostatic hypotension (occasionally with syncope)
• dyspnea
• nausea
• abdominal pain
• Asthenia

Dizziness	Headache	Bradycardia
Hypotension	Nausea	Asthenia

Impaired Hepatic Function: Labetalol Tablets should be used with caution in patients with impaired hepatic function since metabolism of the drug may be diminished.

Dosing with Labetalol Tablets should not be interrupted or discontinued without a physician's advice.

Intraoperative Floppy Iris Syndrome (IFIS) has been observed during cataract surgery in some patients treated with alpha-1 blockers (labetalol is an alpha/beta blocker).