Name Moxifloxacin
Classes Antiinfective Agent
Antibiotic
Topical Antiinfective Agent
Ophthalmic Preparation
Quinolone
Diseases Bronchitis
Infectious Disease
Plague
Pneumonia
Sinusitis

Moxifloxacin

Moxifloxacin is an antibiotic of the fluoroquinolone class. It kills bacteria by inhibiting DNA synthesis. 

Moxifloxacin is used to treat the following infections-

  • Acute bacterial sinusitis
  • Acute exacerbation of chronic obstructive pulmonary disease including bronchitis
  • Community-acquired pneumonia
  • Complicated skin and soft tissue infections
  • Urinary tract infections

The usual dosage is 400mg for up to 14 days. It is available as tablets, ophthalmic drops and IV infusion.

How to reconstitute powder for suspension:

How to apply ophthalmic drops:

The common side effects caused by moxifloxacin include-

  • Nausea and other gastrointestinal disturbances
  • Headache & Dizziness
  • Joint pain
  • Skin rashes
  • Long QT syndrome
  • It can also halt bone and cartilage growth.

 

  • Patients using moxifloxacin should be encouraged to drink plenty of water. 
  • In individuals with suspected or established CNS problems, such as epilepsy, or other variables that predispose to seizures and convulsions, it should be administered with caution. 
  • Avoid in patients with known QT prolongation, hypokalemia.
  • Intravenous administration of moxifloxacin in patients with additional risks may elevate the risk of QT interval prolongation.

Contraindication

  • It is contraindicated in patients who have known hypersensitivity to moxifloxacin or other quinolones such as-
  • Concomitant administration with tizanidine is contraindicated.

Moxifloxacin should not be taken with milk, mineral supplements or antacids.

Moxifloxacin is contraindicated in-

  • Pregnancy & Lactation
  • Children under 18